| Literature DB >> 12868889 |
Kazuyuki Miyashita1, Takayuki Sakai, Takeshi Imanishi.
Abstract
[reaction: see text] The first total synthesis of a marine-derived potent antitumor antibiotic, (+/-)-spiroxin C, was achieved via a TBAF-activated Suzuki-Miyaura cross-coupling reaction as a key step, which was also shown to be useful for the synthesis of sterically hindered binaphthyl derivatives.Entities:
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Year: 2003 PMID： 12868889 DOI： 10.1021/ol034856v
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005