Literature DB >> 12865973

Effects of fucoidan on chronic renal failure in rats.

Quanbin Zhang1, Zhien Li, Zuhong Xu, Xizhen Niu, Hong Zhang.   

Abstract

The effects of fucoidan on chronic renal failure (CRF) were investigated in vivo in a subtotal nephrectomy CRF model and a cryoinjury induced CRF model in rats. Fucoidan showed renoprotective effects in both models. Fucoidan (100 or 200 mg/kg, orally) significantly decreased elevated serum creatinine and urea nitrogen levels. Histopathological changes of renal tubules and interstitium were markedly alleviated by fucoidan and the mesangial areas were also greatly reduced. The activities of fucoidan were dose-dependent.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12865973     DOI： 10.1055/s-2003-40634

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  11 in total

1.  Fucoidan protects against subacute diazinon-induced oxidative damage in cardiac, hepatic, and renal tissues.

Authors:  Mohamed M Abdel-Daim; Abdelrahman Ibrahim Abushouk; Eshak I Bahbah; Simona G Bungău; Mohamed S Alyousif; Lotfi Aleya; Saad Alkahtani
Journal:  Environ Sci Pollut Res Int       Date:  2020-01-21       Impact factor: 4.223

2.  Low molecular weight fucoidan ameliorates diabetic nephropathy via inhibiting epithelial-mesenchymal transition and fibrotic processes.

Authors:  Jihui Chen; Wentong Cui; Quanbin Zhang; Yingli Jia; Yi Sun; Lin Weng; Dali Luo; Hong Zhou; Baoxue Yang
Journal:  Am J Transl Res       Date:  2015-09-15       Impact factor: 4.060

3.  Low molecular weight fucoidan against renal ischemia-reperfusion injury via inhibition of the MAPK signaling pathway.

Authors:  Jihui Chen; Weiling Wang; Quanbin Zhang; Fei Li; Tianluo Lei; Dali Luo; Hong Zhou; Baoxue Yang
Journal:  PLoS One       Date:  2013-02-13       Impact factor: 3.240

Review 4.  Therapies from fucoidan; multifunctional marine polymers.

Authors:  Janet Helen Fitton
Journal:  Mar Drugs       Date:  2011-09-30       Impact factor: 6.085

5.  Oligo-fucoidan prevents renal tubulointerstitial fibrosis by inhibiting the CD44 signal pathway.

Authors:  Cheng-Hsien Chen; Yuh-Mou Sue; Chung-Yi Cheng; Yen-Cheng Chen; Chung-Te Liu; Yung-Ho Hsu; Pai-An Hwang; Nai-Jen Huang; Tso-Hsiao Chen
Journal:  Sci Rep       Date:  2017-01-18       Impact factor: 4.379

6.  Pharmacokinetic and Tissue Distribution of Fucoidan from Fucus vesiculosus after Oral Administration to Rats.

Authors:  Olga N Pozharitskaya; Alexander N Shikov; Natalya M Faustova; Ekaterina D Obluchinskaya; Vera M Kosman; Heikki Vuorela; Valery G Makarov
Journal:  Mar Drugs       Date:  2018-04-18       Impact factor: 5.118

7.  Fucoidan Protects Dopaminergic Neurons by Enhancing the Mitochondrial Function in a Rotenone-induced Rat Model of Parkinson's Disease.

Authors:  Li Zhang; Junwei Hao; Yan Zheng; Ruijun Su; Yajin Liao; Xiaoli Gong; Limin Liu; Xiaomin Wang
Journal:  Aging Dis       Date:  2018-08-01       Impact factor: 6.745

8.  The protective effect of fucoidan in rats with streptozotocin-induced diabetic nephropathy.

Authors:  Jing Wang; Huaide Liu; Ning Li; Quanbin Zhang; Hong Zhang
Journal:  Mar Drugs       Date:  2014-05-30       Impact factor: 5.118

9.  Low molecular weight fucoidan protects renal tubular cells from injury induced by albumin overload.

Authors:  Yingli Jia; Yi Sun; Lin Weng; Yingjie Li; Quanbin Zhang; Hong Zhou; Baoxue Yang
Journal:  Sci Rep       Date:  2016-08-22       Impact factor: 4.379

10.  Fucoidan elevates surface organic cation transporter 2 expression via upregulation of protein kinase A in uric acid nephropathy.

Authors:  Xinlin Wu; Miansheng Yan; Taoli Liu; Jiantang Liao; Jianqing Zhang; Shuqing Chen; Wei Deng; Shijun Zhang; Baoguo Sun; Houming Zhou; Bin Ke
Journal:  Exp Ther Med       Date:  2017-08-30       Impact factor: 2.447
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.