| Literature DB >> 12862452 |
Alex C Comely1, Rienk Eelkema, Adriaan J Minnaard, Ben L Feringa.
Abstract
A novel integrated bio- and chemocatalytic approach to the de novo catalytic asymmetric synthesis of saccharides has been developed. Acetoxypyranones obtained enantiopure by enzymatic resolution have been shown to undergo highly stereoselective palladium-catalyzed formal O-glycoside bond formation. The combination of these protocols can be applied to the iterative asymmetric catalytic synthesis of saccharides.Entities:
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Year: 2003 PMID： 12862452 DOI： 10.1021/ja0347538
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419