Literature DB >> 12860797

Selective laser trabeculoplasty as primary treatment for open-angle glaucoma: a prospective, nonrandomized pilot study.

Shlomo Melamed1, Guy J Ben Simon, Hana Levkovitch-Verbin.   

Abstract

OBJECTIVE: To examine the safety and efficacy of selective laser trabeculoplasty as primary treatment for patients with open-angle glaucoma.
METHODS: Forty-five eyes of 31 patients with open-angle glaucoma or ocular hypertension (intraocular pressure [IOP] >or=23 mm Hg on 2 consecutive measurements) underwent selective laser trabeculoplasty as primary treatment. All patients underwent complete ophthalmic evaluation before and at intervals after treatment. This evaluation included visual acuity, slitlamp examination, ophthalmoscopy, gonioscopy, and visual field analysis. The IOP was measured 1 hour, 1 day, 1 week, and 1, 3, 6, 12, 15, and 18 months postoperatively. During the follow-up period, patients were treated with topical antiglaucoma medications as required.
RESULTS: Mean +/- SD decreased by 7.7 +/- 3.5 mm Hg (30%), from 25.5 +/- 2.5 mm Hg to 17.9 +/- 2.8 mm Hg (P<.001). Only 2 eyes (4%) did not respond to selective laser trabeculoplasty, and 3 eyes (7%) required topical medications to control their IOP at the end of the follow-up period. Forty eyes (89%) had a decrease of 5 mm Hg or more. Visual acuity, visual fields, and gonioscopic findings remained unchanged. Complications included conjunctival redness and injection within 1 day postoperatively in 30 eyes (67%). One hour after selective laser trabeculoplasty, an increase in IOP of more than 5 mm Hg was detected in 5 eyes (11%), while an increase in IOP between 2 and 5 mm Hg was measured in 3 eyes (7%).
CONCLUSION: Selective laser trabeculoplasty is effective and safe as a primary treatment for patients with ocular hypertension and open-angle glaucoma.

Entities:  

Mesh:

Year:  2003        PMID: 12860797     DOI: 10.1001/archopht.121.7.957

Source DB:  PubMed          Journal:  Arch Ophthalmol        ISSN: 0003-9950


  64 in total

1.  Effects of primary selective laser trabeculoplasty on anterior segment parameters.

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Journal:  Int J Ophthalmol       Date:  2015-10-18       Impact factor: 1.779

Review 2.  Discovery of Molecular Therapeutics for Glaucoma: Challenges, Successes, and Promising Directions.

Authors:  Rebecca K Donegan; Raquel L Lieberman
Journal:  J Med Chem       Date:  2015-09-25       Impact factor: 7.446

3.  A randomised, prospective study comparing selective laser trabeculoplasty with latanoprost for the control of intraocular pressure in ocular hypertension and open angle glaucoma.

Authors:  M Nagar; A Ogunyomade; D P S O'Brart; F Howes; J Marshall
Journal:  Br J Ophthalmol       Date:  2005-11       Impact factor: 4.638

4.  Baseline IOP predicts selective laser trabeculoplasty success at 1 year post-treatment: results from a randomised clinical trial.

Authors:  W G Hodge; K F Damji; W Rock; R Buhrmann; A M Bovell; Y Pan
Journal:  Br J Ophthalmol       Date:  2005-09       Impact factor: 4.638

5.  Selective laser trabeculoplasty: predictive value of early intraocular pressure measurements for success at 3 months.

Authors:  P B Johnson; L J Katz; D J Rhee
Journal:  Br J Ophthalmol       Date:  2006-02-07       Impact factor: 4.638

6.  Complete 360° circumferential gonioscopic optical coherence tomography imaging of the iridocorneal angle.

Authors:  Ryan P McNabb; Pratap Challa; Anthony N Kuo; Joseph A Izatt
Journal:  Biomed Opt Express       Date:  2015-03-20       Impact factor: 3.732

7.  Repeatability of primary selective laser trabeculoplasty in patients with primary open-angle glaucoma.

Authors:  Neil Avery; Ghee Soon Ang; Simon Nicholas; Anthony Wells
Journal:  Int Ophthalmol       Date:  2013-01-31       Impact factor: 2.031

8.  Selective laser trabeculoplasty versus argon laser trabeculoplasty: results from a 1-year randomised clinical trial.

Authors:  K F Damji; A M Bovell; W G Hodge; W Rock; K Shah; R Buhrmann; Y I Pan
Journal:  Br J Ophthalmol       Date:  2006-08-09       Impact factor: 4.638

9.  Selective laser trabeculoplasty for elevated intraocular pressure following subtenon injection of triamcinolone acetonide.

Authors:  Kenya Yuki; Makoto Inoue; Daisuke Shiba; Ryosuke Kawamura; Susumu Ishida; Yuichiro Ohtake
Journal:  Clin Ophthalmol       Date:  2010-04-26

10.  Update on laser trabeculoplasty.

Authors:  Fathi El Sayyad; Magdi Helal
Journal:  Middle East Afr J Ophthalmol       Date:  2009-07
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