| Literature DB >> 12860003 |
Richard S Houlston1, Gabrielle Sellick, Martin Yuille, Estella Matutes, Daniel Catovsky.
Abstract
In Western countries B-cell chronic lymphocytic leukemia (CLL) is the most common form of leukemia. Evidence from epidemiological studies and family studies strongly supports the notion that a subset of CLL involves inherited susceptibility. Identification of genes predisposing to CLL should be useful for diagnosis and treatment, as well as serving as a model for B-cell tumorigenesis in general. Here, we review the current status of knowledge about inherited susceptibility to CLL.Entities:
Mesh:
Year: 2003 PMID: 12860003 DOI: 10.1016/s0145-2126(03)00023-7
Source DB: PubMed Journal: Leuk Res ISSN: 0145-2126 Impact factor: 3.156