Literature DB >> 12859704

Five-year prospective analysis of dietary intake and clinical status in malnourished cystic fibrosis patients.

J Walkowiak1, J Przyslawski.   

Abstract

BACKGROUND: Poor growth and malnutrition still pose a problem in cystic fibrosis (CF). The aim of the present study was to assess nutrition, as well as clinical status, of malnourished CF patients during a nutritional care programme.
MATERIAL AND METHODS: The study comprised 38 CF patients, aged 1-18 years old. The prospective annual assessment of dietary intake and clinical status was carried out during 1994-98.
RESULTS: The energy intake increased, in comparison with recommended daily allowances, from 83.6 +/- 4.8% in 1994 to 107.9 +/- 4.9% in 1998. A similar tendency was observed for the percentage of energy derived from fat (30.3 +/- 0.8% versus 35.1 +/- 0.8%) and protein (11.4 +/- 0.4% versus 13.8 +/- 0.4%). In subsequent years of the study, an improvement in the fat profile of the diet (with a higher consumption of polyunsaturated fatty acids) was observed. The observed increase of vitamin A and E consumption was related chiefly to changes in the doses of supplementation. During these 5 years, an improvement in nutritional status (Z-score: height -1.34 +/- 0.13 versus -1.08 +/- 0.14 and weight -1.40 +/- 0.09 versus -1.12 +/- 0.08) and lung function (forced expiratory volume in 1 s: 75.5 +/- 2.0% versus 77.8 +/- 2.2%) was observed.
CONCLUSION: The nutritional care programme resulted in stable quantitative and qualitative changes in dietary intake. Although the diet does not reach the recommended level of high-energy intake, the positive impact of increasing nutrient intake on the nutritional and clinical status of malnourished CF patients was documented.

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Year:  2003        PMID: 12859704     DOI: 10.1046/j.1365-277x.2003.00451.x

Source DB:  PubMed          Journal:  J Hum Nutr Diet        ISSN: 0952-3871            Impact factor:   3.089


  6 in total

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