Literature DB >> 12856284

Cloning, functional study and comparative mapping of Luzp2 to mouse chromosome 7 and human chromosome 11p13-11p14.

Min Wu1, Edward J Michaud, Dabney K Johnson.   

Abstract

A novel leucine-zipper gene, leucine zipper protein 2 (Luzp2), has been cloned as part of an aberrant deletion-fusion transcript in the chromosomal interval between Gas2 and Herc2 on mouse Chromosome 7 (Chr 7). Luzp2 is normally expressed only in brain and spinal cord. The human homolog of Luzp2 maps to Chr 11p13-11p14 by radiation-hybrid mapping and is deleted in some patients with Wilms tumor-Aniridia-Genitourinary anomalies-mental Retardation (WAGR) syndrome. Disruption of Luzp2 by gene targeting in mice did not result in any obvious abnormal phenotypes.

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Year:  2003        PMID： 12856284     DOI： 10.1007/s00335-002-2248-6

Source DB:  PubMed          Journal:  Mamm Genome        ISSN： 0938-8990            Impact factor:   2.957


  18 in total

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4.  Molecular analysis of 36 mutations at the mouse pink-eyed dilution (p) locus.

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Journal:  Genetics       Date:  1995-12       Impact factor: 4.562

5.  Del 11p/aniridia complex. Report of three patients and review of 37 observations from the literature.

Authors:  C Turleau; J de Grouchy; M F Tournade; M F Gagnadoux; C Junien
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6.  Clustering of six human 11p15 gene homologs within a 500-kb interval of proximal mouse chromosome 7.

Authors:  L Stubbs; E M Rinchik; E Goldberg; B Rudy; M A Handel; D Johnson
Journal:  Genomics       Date:  1994-11-15       Impact factor: 5.736

7.  Complementation analyses for 45 mutations encompassing the pink-eyed dilution (p) locus of the mouse.

Authors:  L B Russell; C S Montgomery; N L Cacheiro; D K Johnson
Journal:  Genetics       Date:  1995-12       Impact factor: 4.562

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Authors:  T Glaser; L Jepeal; J G Edwards; S R Young; J Favor; R L Maas
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Authors:  Y Ji; M J Walkowicz; K Buiting; D K Johnson; R E Tarvin; E M Rinchik; B Horsthemke; L Stubbs; R D Nicholls
Journal:  Hum Mol Genet       Date:  1999-03       Impact factor: 6.150

10.  The human BDNF gene maps between FSHB and HVBS1 at the boundary of 11p13-p14.

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3.  Analysis of Association of Genetic Markers in the LUZP2 and FBXO40 Genes with the Normal Variability in Cognitive Performance in the Elderly.

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5.  Leucine zipper protein 2 serves as a prognostic biomarker for prostate cancer correlating with immune infiltration and epigenetic regulation.

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6.  Alterations of androgen receptor-regulated enhancer RNAs (eRNAs) contribute to enzalutamide resistance in castration-resistant prostate cancer.

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7.  Genome-wide association study identifies two loci influencing plasma neurofilament light levels.

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8.  Downregulation of LUZP2 Is Correlated with Poor Prognosis of Low-Grade Glioma.

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  8 in total

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