Literature DB >> 12852963

Novel coumarin derivatives of heterocyclic compounds as lipid-lowering agents.

Gurram R Madhavan1, Vadla Balraju, Bejugam Mallesham, Ranjan Chakrabarti, Vidya B Lohray.   

Abstract

Coumarin derivatives of different heterocycles (5,7a-i, 10 and 11) were designed based on cyclisation of 2-ethoxy-3-phenylpropanoic acid and 2-benzylmalonic acid as novel lipid-lowering agents and their preliminary in vivo screening indicates 7c has moderate triglyceride-lowering activity.

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Year:  2003        PMID： 12852963     DOI： 10.1016/s0960-894x(03)00490-6

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  7 in total

1.  Rotational diffusion and solvatochromic correlation of coumarin 6 laser dye.

Authors:  U S Raikar; C G Renuka; Y F Nadaf; B G Mulimani; A M Karguppikar
Journal:  J Fluoresc       Date:  2006-09-22       Impact factor: 2.217

Review 2.  A review of coumarin derivatives in pharmacotherapy of breast cancer.

Authors:  Musiliyu A Musa; John S Cooperwood; M Omar F Khan
Journal:  Curr Med Chem       Date:  2008       Impact factor: 4.530

3.  Evaluation of the hypolipidemic activity of 6,7-dimethoxycoumarin on placental tissue factor mRNA expression in experimental anti-phospholipid syndrome.

Authors:  Annamalai Amarnath; Veeraval Lenin; Govindaraju Archunan
Journal:  Pharmacogn Mag       Date:  2013-07       Impact factor: 1.085

4.  Design, synthesis, DFT, docking studies and ADME prediction of some new coumarinyl linked pyrazolylthiazoles: Potential standalone or adjuvant antimicrobial agents.

Authors:  Sunil Kumar; Vikram Saini; Indresh K Maurya; Jayant Sindhu; Mukesh Kumari; Ramesh Kataria; Vinod Kumar
Journal:  PLoS One       Date:  2018-04-19       Impact factor: 3.240

5.  ZnCl2 catalyzed new coumarinyl-chalcones as cytotoxic agents.

Authors:  Konidala Sathish Kumar; Vijay Kotra; Ch B Praveena Devi; Nutakki Anusha; Bollikolla Hari Babu; Syed Farooq Adil; Mohammed Rafi Shaik; Mujeeb Khan; Abdulrahman Al-Warthan; Osamah Alduhaish; M Mujahid Alam
Journal:  Saudi J Biol Sci       Date:  2020-10-22       Impact factor: 4.219

6.  Radical Scavenging Activity and Pharmacokinetic Properties of Coumarin-Hydroxybenzohydrazide Hybrids.

Authors:  Marko R Antonijević; Edina H Avdović; Dušica M Simijonović; Žiko B Milanović; Ana D Amić; Zoran S Marković
Journal:  Int J Mol Sci       Date:  2022-01-01       Impact factor: 5.923

7.  Deactivation of 6-aminocoumarin intramolecular charge transfer excited state through hydrogen bonding.

Authors:  Ewa Krystkowiak; Krzysztof Dobek; Andrzej Maciejewski
Journal:  Int J Mol Sci       Date:  2014-09-19       Impact factor: 5.923
  7 in total

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