Literature DB >> 12852961

Discovery of the first series of inhibitors of human papillomavirus type 11: inhibition of the assembly of the E1-E2-Origin DNA complex.

Christiane Yoakim1, William W Ogilvie, Nathalie Goudreau, Julie Naud, Bruno Haché, Jeff A O'Meara, Michael G Cordingley, Jacques Archambault, Peter W White.   

Abstract

We have discovered a series of inhibitors of the assembly of the HPV11 E1-E2-origin DNA complex, which incorporate an indandione fused to a substituted tetrahydrofuran.

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Year:  2003        PMID： 12852961     DOI： 10.1016/s0960-894x(03)00510-9

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  10 in total

1.  Identification and characterization of small molecule antagonists of pRb inactivation by viral oncoproteins.

Authors:  Daniela Fera; David C Schultz; Santosh Hodawadekar; Melvin Reichman; Preston Scott Donover; Jason Melvin; Scott Troutman; Joseph L Kissil; Donna M Huryn; Ronen Marmorstein
Journal:  Chem Biol       Date:  2012-04-20

Review 2.  Targeting human papillomavirus genome replication for antiviral drug discovery.

Authors:  Jacques Archambault; Thomas Melendy
Journal:  Antivir Ther       Date:  2013-04-24

Review 3.  Development of Protein-Protein Interaction Inhibitors for the Treatment of Infectious Diseases.

Authors:  Andrew F Voter; James L Keck
Journal:  Adv Protein Chem Struct Biol       Date:  2017-08-24       Impact factor: 3.507

Review 4.  Recent advances in the search for antiviral agents against human papillomaviruses.

Authors:  Amélie Fradet-Turcotte; Jacques Archambault
Journal:  Antivir Ther       Date:  2007

5.  Structural characterization and comparison of three acyl-carrier-protein synthases from pathogenic bacteria.

Authors:  Andrei S Halavaty; Youngchang Kim; George Minasov; Ludmilla Shuvalova; Ievgeniia Dubrovska; James Winsor; Min Zhou; Olena Onopriyenko; Tatiana Skarina; Leka Papazisi; Keehwan Kwon; Scott N Peterson; Andrzej Joachimiak; Alexei Savchenko; Wayne F Anderson
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2012-09-13

6.  Small molecule inhibitors of human papillomavirus protein - protein interactions.

Authors:  C M D'Abramo; J Archambault
Journal:  Open Virol J       Date:  2011-07-04

7.  Identification of several high-risk HPV inhibitors and drug targets with a novel high-throughput screening assay.

Authors:  Mart Toots; Mart Ustav; Andres Männik; Karl Mumm; Kaido Tämm; Tarmo Tamm; Ene Ustav; Mart Ustav
Journal:  PLoS Pathog       Date:  2017-02-09       Impact factor: 6.823

8.  Discovery of novel West Nile Virus protease inhibitor based on isobenzonafuranone and triazolic derivatives of eugenol and indan-1,3-dione scaffolds.

Authors:  André S de Oliveira; Poliana A R Gazolla; Ana Flávia C da S Oliveira; Wagner L Pereira; Lívia C de S Viol; Angélica F da S Maia; Edjon G Santos; Ítalo E P da Silva; Tiago A de Oliveira Mendes; Adalberto M da Silva; Roberto S Dias; Cynthia C da Silva; Marcelo D Polêto; Róbson R Teixeira; Sergio O de Paula
Journal:  PLoS One       Date:  2019-09-26       Impact factor: 3.240

Review 9.  The Reservoir of Persistent Human Papillomavirus Infection; Strategies for Elimination Using Anti-Viral Therapies.

Authors:  Ke Zheng; Nagayasu Egawa; Aslam Shiraz; Mayako Katakuse; Maki Okamura; Heather M Griffin; John Doorbar
Journal:  Viruses       Date:  2022-01-22       Impact factor: 5.048

Review 10.  New Insights Into DNA Helicases as Druggable Targets for Cancer Therapy.

Authors:  Arindam Datta; Robert M Brosh
Journal:  Front Mol Biosci       Date:  2018-06-26
  10 in total

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