Literature DB >> 12851477

Cell immortality and hallmarks of cancer.

Mikhail V Blagosklonny1.   

Abstract

In growth-limiting conditions, cells that express telomerase and inactivate tumor suppressors have a selective advantage due to resistance to growth arrest. Accidentally such cells become immortal.

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Year:  2003        PMID： 12851477

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


  15 in total

1.  Differential regulation of human YY1 and caspase 7 promoters by prohibitin through E2F1 and p53 binding sites.

Authors:  B Joshi; S Rastogi; M Morris; L M Carastro; C DeCook; E Seto; S P Chellappan
Journal:  Biochem J       Date:  2007-01-01       Impact factor: 3.857

2.  Pregnane X receptor activation induces FGF19-dependent tumor aggressiveness in humans and mice.

Authors:  Hongwei Wang; Madhukumar Venkatesh; Hao Li; Regina Goetz; Subhajit Mukherjee; Arunima Biswas; Liang Zhu; Andreas Kaubisch; Lei Wang; James Pullman; Kathleen Whitney; Makoto Kuro-o; Andres I Roig; Jerry W Shay; Moosa Mohammadi; Sridhar Mani
Journal:  J Clin Invest       Date:  2011-07-11       Impact factor: 14.808

3.  Defined genetic events associated with the spontaneous in vitro transformation of ElA/Ras-expressing human IMR90 fibroblasts.

Authors:  Douglas X Mason; Daniel Keppler; Jun Zhang; Tonya J Jackson; Yvette R Seger; Seiichi Matsui; Fleurette Abreo; John K Cowell; Gregory J Hannon; Scott W Lowe; Athena W Lin
Journal:  Carcinogenesis       Date:  2005-11-09       Impact factor: 4.944

4.  Is cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism.

Authors:  Adam Ertel; Aristotelis Tsirigos; Diana Whitaker-Menezes; Ruth C Birbe; Stephanos Pavlides; Ubaldo E Martinez-Outschoorn; Richard G Pestell; Anthony Howell; Federica Sotgia; Michael P Lisanti
Journal:  Cell Cycle       Date:  2012-01-15       Impact factor: 4.534

5.  Telomere-dependent and telomere-independent origins of endogenous DNA damage in tumor cells.

Authors:  Asako J Nakamura; Christophe E Redon; William M Bonner; Olga A Sedelnikova
Journal:  Aging (Albany NY)       Date:  2009-02-04       Impact factor: 5.682

6.  Haematoporphyrin based photodynamic therapy combined with hyperthermia provided effective therapeutic vaccine effect against colon cancer growth in mice.

Authors:  Yaoming He; Haiyan Ge; Shuping Li
Journal:  Int J Med Sci       Date:  2012-09-19       Impact factor: 3.738

7.  Molecular damage in cancer: an argument for mTOR-driven aging.

Authors:  Mikhail V Blagosklonny
Journal:  Aging (Albany NY)       Date:  2011-12       Impact factor: 5.682

8.  Just like the rest of evolution in Mother Nature, the evolution of cancers may be driven by natural selection, and not by haphazard mutations.

Authors:  Ju Zhang; Xiaomin Lou; Lucas Zellmer; Siqi Liu; Ningzhi Xu; D Joshua Liao
Journal:  Oncoscience       Date:  2014-09-22

9.  Immortality of cancers: a consequence of inherent karyotypic variations and selections for autonomy.

Authors:  Peter Duesberg; Amanda McCormack
Journal:  Cell Cycle       Date:  2013-02-06       Impact factor: 4.534

Review 10.  TGF-β cascade regulation by PPP1 and its interactors -impact on prostate cancer development and therapy.

Authors:  Luís Korrodi-Gregório; Joana Vieira Silva; Luís Santos-Sousa; Maria João Freitas; Juliana Felgueiras; Margarida Fardilha
Journal:  J Cell Mol Med       Date:  2014-03-15       Impact factor: 5.310
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