| Literature DB >> 12851293 |
Victor J Hruby1, Minying Cai, Paolo Grieco, Guoxia Han, Malcolm Kavarana, Dev Trivedi.
Abstract
The melanotropin peptides alpha-MSH, gamma-MSH, and beta-MSH are believed to be the natural ligands for the four melanocortin receptors, MC1R, MC3R, MC4R, and MC5R. However, these peptides generally have low selectivity for these receptors. We report on some approaches to the development of selective agonists and antagonists peptide ligands for these receptors.Entities:
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Year: 2003 PMID: 12851293 DOI: 10.1111/j.1749-6632.2003.tb03157.x
Source DB: PubMed Journal: Ann N Y Acad Sci ISSN: 0077-8923 Impact factor: 5.691