| Literature DB >> 12849975 |
Takeshi Nabeshima1, Toshinori Kozaki, Takashi Tomita, Yoshiaki Kono.
Abstract
cDNAs encoding two acetylcholinesterases (AChEs) were isolated from the peach potato aphid, Myzus persicae. MpAChE1 was orthologous and MpAChE2 was paralogous with the ace of Drosophila melanogaster. The deduced amino acid sequence of MpAChE1 cDNA was identical between the pirimicarb susceptible and resistant strains. However, a single amino acid substitution of Ser431Phe on MpAchE2 was found in the pirimicarb resistant strains. This substitution was located in the acyl pocket of the enzyme and was thought to alter the ligand specificity.Entities:
Mesh:
Substances:
Year: 2003 PMID: 12849975 DOI: 10.1016/s0006-291x(03)01101-x
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN: 0006-291X Impact factor: 3.575