| Literature DB >> 12848959 |
M A M van Boekel1, W J van Venrooij.
Abstract
Posttranslational modifications of proteins often perform a key role in the biological functioning of proteins. Some of these modifications also change the immunogenicity of proteins and peptides and create 'self'-antigens which might induce autoimmune responses. In particular modifications of arginines within a defined protein context can lead to a specific B-cell immune response. This review discusses the generation of such modifications and their relevance for autoimmunity.Entities:
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Year: 2003 PMID： 12848959 DOI： 10.1016/s1568-9972(02)00128-3
Source DB: PubMed Journal: Autoimmun Rev ISSN： 1568-9972 Impact factor: 9.754