Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The solubility properties of granulopoiesis inhibiting factor.

Literature DB >> 128468

The solubility properties of granulopoiesis inhibiting factor.

Abstract

The solubility of granulopoiesis inhibiting factor (GIF) in various aqueous and organic solvents was investigated. GIF is soluble in water, 10% acetic acid, and 10% pyridine. It is not extractable by 1-butanol at low and high pH. A high solubility was found in polar organic solvents (ethanol-acetone 9:1, and chloroform-methanol 1:1), whereas GIF seems to be insoluble in pure chloroform.

Entities: Chemical

Mesh：

Substances：

Year: 1975 PMID： 128468 DOI： 10.1007/bf01945825

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

Keyword Cloud
References

13 in total

1. Proliferation kinetics of myelopoietic cells and macrophages in diffusion chambers after treatment with granulocyte extracts (chalone).

Authors: O D Laerum; H R Maurer
Journal: Virchows Arch B Cell Pathol Date: 1973-12-17

2. Cell specificity of chalone-type inhibitors of DNA synthesis released by blood leucocytes and erythrocytes.

Authors: A E Bateman
Journal: Cell Tissue Kinet Date: 1974-09

3. Inhibition of granulopoiesis by endogenous granulocyte chalone studied with the diffusion chamber technique.

Authors: J A Vilpo; K Kiviniemi; T Rytömaa
Journal: Eur J Cancer Date: 1973-07 Impact factor: 9.162

4. Granulopoiesis-inhibiting factor: demonstration and preliminary chemical and biological characterization of a specific polypeptide (chalone).

Authors: W R Paukovits
Journal: Natl Cancer Inst Monogr Date: 1973-07

5. Control of granulocyte production: separation and chemical identification of a specific inhibitor (chalone).

Authors: W R Paukovits
Journal: Cell Tissue Kinet Date: 1971-11

6. The isolation of erythropoiesis regulatory factory by an electrofractionation technique combined with selective membrane permeability.

Authors: J P Lewis; W A Neal; E T Welch; W G Lewis; C M DuBose; C S Wright; L L Smith
Journal: Proc Soc Exp Biol Med Date: 1973-01

The solubility properties of granulopoiesis inhibiting factor.

1. Proliferation kinetics of myelopoietic cells and macrophages in diffusion chambers after treatment with granulocyte extracts (chalone).

2. Cell specificity of chalone-type inhibitors of DNA synthesis released by blood leucocytes and erythrocytes.

3. Inhibition of granulopoiesis by endogenous granulocyte chalone studied with the diffusion chamber technique.

4. Granulopoiesis-inhibiting factor: demonstration and preliminary chemical and biological characterization of a specific polypeptide (chalone).

5. Control of granulocyte production: separation and chemical identification of a specific inhibitor (chalone).

6. The isolation of erythropoiesis regulatory factory by an electrofractionation technique combined with selective membrane permeability.

7. Rapid screening of macromolecular synthesis in single cell cultures.

8. Isolation, purification, and properties of porcine calcitonins.

9. Biosynthesis of melittin, a toxic peptide from bee venom. Detection of a possible precursor.

10. An in vitro micromethod for testing cytotoxic compounds.