OBJECTIVE: A case-control study was conducted to examine the association of weight and length at birth with early-onset prostate cancer. METHODS: Cases of prostate cancer diagnosed between 1988 and 1995 (n = 192) were identified through the Minnesota Cancer Surveillance System. Two separate control groups were selected using driver's license (DL) and birth certificate (BC) listings. RESULTS: Using the DL control group, an inverse association was observed between birth weight and prostate cancer risk; adjusted odds ratios (95% confidence intervals) for < or = 3000, 3001-3500, 3501-4000, and > 4000 g at birth were 1.0, 0.72 (0.40-1.28), 0.58 (0.31-1.10), and 0.49 (0.24-1.00). In analyses using the BC control group, adjusted odds ratios (95% CIs) for the aforementioned birth weight categories were 1.0, 1.18 (0.64-2.18), 0.80 (0.42-1.54), and 1.04 (0.48-2.26), respectively. For both control groups, adjusted odds ratios were somewhat elevated for the upper three categories of birth length, but all confidence intervals included the null value. CONCLUSIONS: These findings do not support the hypothesis that greater weight or length at birth increases risk of prostate cancer.
OBJECTIVE: A case-control study was conducted to examine the association of weight and length at birth with early-onset prostate cancer. METHODS: Cases of prostate cancer diagnosed between 1988 and 1995 (n = 192) were identified through the Minnesota Cancer Surveillance System. Two separate control groups were selected using driver's license (DL) and birth certificate (BC) listings. RESULTS: Using the DL control group, an inverse association was observed between birth weight and prostate cancer risk; adjusted odds ratios (95% confidence intervals) for < or = 3000, 3001-3500, 3501-4000, and > 4000 g at birth were 1.0, 0.72 (0.40-1.28), 0.58 (0.31-1.10), and 0.49 (0.24-1.00). In analyses using the BC control group, adjusted odds ratios (95% CIs) for the aforementioned birth weight categories were 1.0, 1.18 (0.64-2.18), 0.80 (0.42-1.54), and 1.04 (0.48-2.26), respectively. For both control groups, adjusted odds ratios were somewhat elevated for the upper three categories of birth length, but all confidence intervals included the null value. CONCLUSIONS: These findings do not support the hypothesis that greater weight or length at birth increases risk of prostate cancer.
Authors: Michael B Cook; Michael Gamborg; Julie Aarestrup; Thorkild I A Sørensen; Jennifer L Baker Journal: Cancer Epidemiol Biomarkers Prev Date: 2013-10-02 Impact factor: 4.254
Authors: William C Strohsnitter; Marianne Hyer; Kimberly A Bertrand; Andrea L Cheville; Julie R Palmer; Elizabeth E Hatch; Kjersti M Aagaard; Linda Titus; Iris L Romero; Dezheng Huo; Robert N Hoover; Rebecca Troisi Journal: Cancer Epidemiol Biomarkers Prev Date: 2021-07-16 Impact factor: 4.254