Literature DB >> 12845804

[Antiviral activity of some 5-arylethynyl 2'-deoxyuridine derivatives].

V L Andronova1, M V Skorobogatyĭ, E V Manasova, Iu A Berlin, V A Korshun, G A Galegov.   

Abstract

5-(3-Perylenylethynyl)-2'-deoxyuridine was prepared by cross-linking 5-iodo-2'-deoxyuridine derivatives with 3-ethynylperylene followed by deprotection. 5-(1-Perylenylethynyl)-, 5-(3-perylenylethynyl)-, and 5-[4-(2-benzoxazolyl)phenylethynyl]-2'-deoxyuridine were found to inhibit in Vero cells the replication of type 1 herpes simplex virus and its drug-resistant strains.

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Year:  2003        PMID： 12845804     DOI： 10.1023/a:1023936516589

Source DB:  PubMed          Journal:  Bioorg Khim        ISSN： 0132-3423


  4 in total

1.  Rigid amphipathic fusion inhibitors, small molecule antiviral compounds against enveloped viruses.

Authors:  Mireille R St Vincent; Che C Colpitts; Alexey V Ustinov; Muhammad Muqadas; Michael A Joyce; Nicola L Barsby; Raquel F Epand; Richard M Epand; Stanislav A Khramyshev; Olga A Valueva; Vladimir A Korshun; D Lorne J Tyrrell; Luis M Schang
Journal:  Proc Natl Acad Sci U S A       Date:  2010-09-07       Impact factor: 11.205

2.  5-(Perylen-3-yl)ethynyl-arabino-uridine (aUY11), an arabino-based rigid amphipathic fusion inhibitor, targets virion envelope lipids to inhibit fusion of influenza virus, hepatitis C virus, and other enveloped viruses.

Authors:  Che C Colpitts; Alexey V Ustinov; Raquel F Epand; Richard M Epand; Vladimir A Korshun; Luis M Schang
Journal:  J Virol       Date:  2013-01-02       Impact factor: 5.103

3.  Ramified derivatives of 5-(perylen-3-ylethynyl)uracil-1-acetic acid and their antiviral properties.

Authors:  Ksenia A Sapozhnikova; Nikita A Slesarchuk; Alexey A Orlov; Evgeny V Khvatov; Eugene V Radchenko; Alexey A Chistov; Alexey V Ustinov; Vladimir A Palyulin; Liubov I Kozlovskaya; Dmitry I Osolodkin; Vladimir A Korshun; Vladimir A Brylev
Journal:  RSC Adv       Date:  2019-08-20       Impact factor: 4.036

Review 4.  Photosensitizing Antivirals.

Authors:  Kseniya A Mariewskaya; Anton P Tyurin; Alexey A Chistov; Vladimir A Korshun; Vera A Alferova; Alexey V Ustinov
Journal:  Molecules       Date:  2021-06-29       Impact factor: 4.411
  4 in total

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