Literature DB >> 12843896

[Proliferative retinal vasculitis and multiple sclerosis: a case report].

M Patte1, F N Rouher, D Vernay, J-C Delaire, F Bacin.   

Abstract

INTRODUCTION: Retinal periphlebitis can precede the neurological effects of multiple sclerosis and reveal the disease. Although these occurrences of vasculitis are noted in 10% - 35% of multiple sclerosis patients, proliferative retinopathy is, on the contrary, an exceptional complication. CASE REPORT: We report the case of a 28-year-old woman who presented bilateral, proliferative, retinal vasculitis complicated with recurrent vitreous hemorrhages occurring with multiple sclerosis. Initially, there was a unilateral, central venous thrombosis in a particularly ischemic and proliferative form. After a neurological, biological and radiological check-up, the diagnosis of multiple sclerosis was pronounced and treatment with Interferon was started. A pan-retinal laser photocoagulation and vitrectomy with proliferative membrane peeling were performed. After a follow-up of 2.5 years, a bilateral epiretinal membrane on the macula with a chronic macular edema persisted, with visual acuity limited to 0.2 Parinaud 4 in the right eye and 0.5 Parinaud 2 in the left eye. DISCUSSION: This case shows that the diagnosis of multiple sclerosis must be established in cases of ischemic retinal vasculitis, especially as the literature does not seem to report a correlation between the retinal vascular affect and how far multiple sclerosis has progressed. Moreover, the visual prognosis of these proliferative lesions remains uncertain.
CONCLUSION: Multiple sclerosis can be revealed initially, although exceptionally, by bilateral, proliferative and severe retinal vasculitis complicated with recurrent vitreous hemorrhages and tractional retinal detachment.

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Year:  2003        PMID: 12843896

Source DB:  PubMed          Journal:  J Fr Ophtalmol        ISSN: 0181-5512            Impact factor:   0.818


  3 in total

1.  Bilateral Anterior and Intermediate Uveitis with Occlusive Vasculitis as Sole Manifestation of Relapse in Multiple Sclerosis.

Authors:  Angelica Pedraza-Concha; Karin Brandauer; Alejandro Tello; Carlos Mario Rangel; Christian Scheib
Journal:  Case Rep Ophthalmol Med       Date:  2019-07-22

Review 2.  Ischemic retinal vasculitis and its management.

Authors:  Lazha Talat; Sue Lightman; Oren Tomkins-Netzer
Journal:  J Ophthalmol       Date:  2014-04-15       Impact factor: 1.909

3.  No excess of mitochondrial DNA deletions within muscle in progressive multiple sclerosis.

Authors:  Graham R Campbell; Amy K Reeve; Iryna Ziabreva; Richard Reynolds; Doug M Turnbull; Don J Mahad
Journal:  Mult Scler       Date:  2013-06-20       Impact factor: 6.312

  3 in total

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