UNLABELLED: The purpose of this study was to compare (18)F-FDG PET to CT for evaluating the spleen during the initial staging of lymphoma. METHODS: Seven patients with newly diagnosed lymphoma underwent (18)F-FDG PET and CT. Splenic uptake of (18)F-FDG, diffuse or focal, greater than hepatic uptake was interpreted as consistent with tumor. CT demonstrating a positive splenic index or focal hypodensities was classified as positive for tumor. PET and CT results were compared with final diagnoses, which were confirmed surgically for 6 patients and at autopsy for 1 patient. RESULTS: Five of 7 patients had lymphomatous involvement of the spleen. (18)F-FDG PET was true-positive for all 5 patients with splenic disease and true-negative for both patients without splenic disease. CT, in contrast, was true-positive for 4 of the 5 patients with splenic disease and false-positive for the 2 patients without splenic disease. The accuracies of (18)F-FDG PET and CT for evaluating the spleen were 100% and 57%, respectively. CONCLUSION: (18)F-FDG PET correctly identified all patients with and without splenic disease and was superior to CT for this purpose.
UNLABELLED: The purpose of this study was to compare (18)F-FDG PET to CT for evaluating the spleen during the initial staging of lymphoma. METHODS: Seven patients with newly diagnosed lymphoma underwent (18)F-FDG PET and CT. Splenic uptake of (18)F-FDG, diffuse or focal, greater than hepatic uptake was interpreted as consistent with tumor. CT demonstrating a positive splenic index or focal hypodensities was classified as positive for tumor. PET and CT results were compared with final diagnoses, which were confirmed surgically for 6 patients and at autopsy for 1 patient. RESULTS: Five of 7 patients had lymphomatous involvement of the spleen. (18)F-FDG PET was true-positive for all 5 patients with splenic disease and true-negative for both patients without splenic disease. CT, in contrast, was true-positive for 4 of the 5 patients with splenic disease and false-positive for the 2 patients without splenic disease. The accuracies of (18)F-FDG PET and CT for evaluating the spleen were 100% and 57%, respectively. CONCLUSION: (18)F-FDG PET correctly identified all patients with and without splenic disease and was superior to CT for this purpose.
Authors: Christian Philipp Reinert; Clemens Hinterleitner; Jan Fritz; Konstantin Nikolaou; Marius Horger Journal: Eur Radiol Date: 2018-06-18 Impact factor: 5.315
Authors: S S Saboo; K M Krajewski; K N O'Regan; A Giardino; J R Brown; N Ramaiya; J P Jagannathan Journal: Br J Radiol Date: 2011-11-17 Impact factor: 3.039
Authors: Shonit Punwani; King Kenneth Cheung; Nicholas Skipper; Nichola Bell; Alan Bainbridge; Stuart A Taylor; Ashley M Groves; Sharon F Hain; Simona Ben-Haim; Ananth Shankar; Stephen Daw; Steve Halligan; Paul D Humphries Journal: Pediatr Radiol Date: 2013-02-03
Authors: Josephine N Rini; Rodolfo Núñez; Kenneth Nichols; Gene G Tronco; Maria Bernadette Tomas; Diane Hart; Gungor Karayalcin; John C Leonidas; Christopher J Palestro Journal: Pediatr Radiol Date: 2004-11-12