| Literature DB >> 12842138 |
Braulio M Fraga1, Melchor G Hernández, Jose M Artega, Sergio Suárez.
Abstract
The microbiological transformation of dehydroabietanol (18-hydroxy-dehydroabietane) by Mucor plumbeus led to 2alpha,18-dihydroxy-abieta-8,11,13,15-tetraene, 2alpha,15-dihydroxy-dehydroabietanol, 2alpha-hydroxy-15-methoxy-dehydroabietanol, 7beta-hydroxy-2-oxo-dehydroabietanol, 15-hydroxy-2-oxo-dehydroabietanol and 15,16-dihydroxy-2-oxo-dehydroabietanol, whilst that of teideadiol (1alpha,18-dihydroxy-dehydroabietane) gave 2alpha-hydroxy-teideadiol, 7alpha-hydroxy-teideadiol and 7beta-hydroxy-teideadiol. Thus, 2alpha- and 7beta-hydroxylation occur in both biotransformations and the 15-hydroxylation is inhibited in the biotransformation of teideadiol by the presence of a 1alpha-alcohol.Entities:
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Year: 2003 PMID: 12842138 DOI: 10.1016/s0031-9422(03)00291-7
Source DB: PubMed Journal: Phytochemistry ISSN: 0031-9422 Impact factor: 4.072