Literature DB >> 12841249

Reactivity of 2-acylaminoacrylates with ketene diethyl acetal; [2 + 2] cycloadditions vs. tandem condensations.

Alberto Avenoza1, Jesús H Busto, Noelia Canal, Jesús M Peregrina.   

Abstract

The reactivity of 2-acylaminoacrylates with ketene diethyl acetal can be modulated by means of thermal conditions to yield cyclobutanes for the preparation of protected beta-hydroxycyclobutane-alpha-amino acids, or catalytic conditions that yield cyclohexanes by tandem condensations to obtain interesting building blocks that are alternatives to Danishefsky's diene.

Entities:  

Year:  2003        PMID: 12841249

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  Recent Progress on the Stereoselective Synthesis of Cyclic Quaternary alpha-Amino Acids.

Authors:  Carlos Cativiela; Mario Ordóñez
Journal:  Tetrahedron Asymmetry       Date:  2009-01-30

2.  Catalytic synthesis of (E)-alpha,beta-unsaturated esters from aldehydes and 1,1-diethoxyethylene.

Authors:  Rubén Manzano; Lidia Ozores; Andreas Job; Lars Rodefeld; Benjamin List
Journal:  Beilstein J Org Chem       Date:  2009-01-30       Impact factor: 2.883

  2 in total

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