Literature DB >> 12841233

Aziridinyl anions from a chiral, nonracemic 2-isopropylidineaziridine: surprisingly diastereoselective alkylation reactions.

J F Hayes1, N Prévost, I Prokes, M Shipman, A M Z Slawin, H Twin.   

Abstract

Lithiation and alkylation of a 2-isopropylidineaziridine bearing an (S)-alpha-methylbenzyl group on nitrogen proceeds with high levels of diastereocontrol (80-90% de).

Entities:  

Year:  2003        PMID: 12841233     DOI: 10.1039/b303252c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

Review 1.  Synthesis and applications of methyleneaziridines.

Authors:  Bin Pan; Feng Li; Yingying Zhao
Journal:  RSC Adv       Date:  2020-10-27       Impact factor: 4.036

  1 in total

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