Literature DB >> 12840540

Aberrant protein folding as the molecular basis of cancer.

Melissa D Scott1, Judith Frydman.   

Abstract

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Year:  2003        PMID： 12840540     DOI： 10.1385/1-59259-394-1:67

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


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  13 in total

1.  Pathogenic proline mutation in the linker between spectrin repeats: disease caused by spectrin unfolding.

Authors:  Colin P Johnson; Massimiliano Gaetani; Vanessa Ortiz; Nishant Bhasin; Sandy Harper; Patrick G Gallagher; David W Speicher; Dennis E Discher
Journal:  Blood       Date:  2006-12-27       Impact factor: 22.113

2.  The ubiquitin ligase E6-AP is induced and recruited to aggresomes in response to proteasome inhibition and may be involved in the ubiquitination of Hsp70-bound misfolded proteins.

Authors:  Amit Mishra; Swetha K Godavarthi; Megha Maheshwari; Anand Goswami; Nihar Ranjan Jana
Journal:  J Biol Chem       Date:  2009-02-20       Impact factor: 5.157

3.  4.0-A resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement.

Authors:  Yao Cong; Matthew L Baker; Joanita Jakana; David Woolford; Erik J Miller; Stefanie Reissmann; Ramya N Kumar; Alyssa M Redding-Johanson; Tanveer S Batth; Aindrila Mukhopadhyay; Steven J Ludtke; Judith Frydman; Wah Chiu
Journal:  Proc Natl Acad Sci U S A       Date:  2010-03-01       Impact factor: 11.205

Review 4.  Proteomics: a strategy to understand the novel targets in protein misfolding and cancer therapy.

Authors:  Nagathihalli S Nagaraj; Om V Singh; Nipun B Merchant
Journal:  Expert Rev Proteomics       Date:  2010-08       Impact factor: 3.940

5.  Small molecule DnaK modulators targeting the beta-domain.

Authors:  Jason Cellitti; Ziming Zhang; Si Wang; Bainan Wu; Hongbin Yuan; Patty Hasegawa; Donald G Guiney; Maurizio Pellecchia
Journal:  Chem Biol Drug Des       Date:  2009-08-20       Impact factor: 2.817

6.  Hsp70 translocates to the nuclei and nucleoli, binds to XRCC1 and PARP-1, and protects HeLa cells from single-strand DNA breaks.

Authors:  Polychronis Kotoglou; Alexandros Kalaitzakis; Patra Vezyraki; Theodore Tzavaras; Lampros K Michalis; Francoise Dantzer; Jae U Jung; Charalampos Angelidis
Journal:  Cell Stress Chaperones       Date:  2008-12-17       Impact factor: 3.667

7.  Hsp70 regulates the doxorubicin-mediated heart failure in Hsp70-transgenic mice.

Authors:  Katerina Naka K; Patra Vezyraki; Alexandros Kalaitzakis; Stelios Zerikiotis; Lampros Michalis; Charalampos Angelidis
Journal:  Cell Stress Chaperones       Date:  2014-04-20       Impact factor: 3.667

Review 8.  Parkinson's disease and cancer: two wars, one front.

Authors:  Michael J Devine; Hélène Plun-Favreau; Nicholas W Wood
Journal:  Nat Rev Cancer       Date:  2011-10-24       Impact factor: 60.716

9.  Secretion of novel SEL1L endogenous variants is promoted by ER stress/UPR via endosomes and shed vesicles in human cancer cells.

Authors:  Monica Cattaneo; Lavinia Vittoria Lotti; Simone Martino; Massimo Alessio; Antonio Conti; Angela Bachi; Renato Mariani-Costantini; Ida Biunno
Journal:  PLoS One       Date:  2011-02-17       Impact factor: 3.240

10.  Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent.

Authors:  Tomohisa Horibe; Masayuki Kohno; Mari Haramoto; Koji Ohara; Koji Kawakami
Journal:  J Transl Med       Date:  2011-01-14       Impact factor: 5.531
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