Literature DB >> 12839859

Squalene synthase inhibitors.

V C Menys1, P N Durrington.   

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Year:  2003        PMID： 12839859      PMCID： PMC1573925          DOI： 10.1038/sj.bjp.0705331

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


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  11 in total

1.  Inhibition of cholesterol synthesis by squalene synthase inhibitors does not induce myotoxicity in vitro.

Authors:  O P Flint; B A Masters; R E Gregg; S K Durham
Journal:  Toxicol Appl Pharmacol       Date:  1997-07       Impact factor: 4.219

2.  Cataracts in patients treated with triparanol.

Authors:  R C LAUGHLIN; T F CAREY
Journal:  JAMA       Date:  1962-07-28       Impact factor: 56.272

3.  The rule of 5 and the rule of 7 in lipid-lowering by statin drugs.

Authors:  W C Roberts
Journal:  Am J Cardiol       Date:  1997-07-01       Impact factor: 2.778

Review 4.  Sterols and isoprenoids: signaling molecules derived from the cholesterol biosynthetic pathway.

Authors:  P A Edwards; J Ericsson
Journal:  Annu Rev Biochem       Date:  1999       Impact factor: 23.643

Review 5.  Cholesterol and coronary heart disease. A new era.

Authors:  S M Grundy
Journal:  JAMA       Date:  1986-11-28       Impact factor: 56.272

Review 6.  BAREing it all: the adoption of LXR and FXR and their roles in lipid homeostasis.

Authors:  Peter A Edwards; Heidi R Kast; Andrew M Anisfeld
Journal:  J Lipid Res       Date:  2002-01       Impact factor: 5.922

7.  Plasma mevalonic acid, an index of cholesterol synthesis in vivo, and responsiveness to HMG-CoA reductase inhibitors in familial hypercholesterolaemia.

Authors:  R P Naoumova; A D Marais; J Mountney; J C Firth; N B Rendell; G W Taylor; G R Thompson
Journal:  Atherosclerosis       Date:  1996-01-26       Impact factor: 5.162

Review 8.  Ezetimibe: the first in a novel class of selective cholesterol-absorption inhibitors.

Authors:  Eric K Gupta; Matthew K Ito
Journal:  Heart Dis       Date:  2002 Nov-Dec

9.  Ineffective decrease of serum cholesterol by simvastatin in a subgroup of hypercholesterolemic coronary patients.

Authors:  Tatu A Miettinen; Helena Gylling
Journal:  Atherosclerosis       Date:  2002-09       Impact factor: 5.162

10.  Interrelations of lipids and lipoproteins with coronary artery disease mortality in 19 countries.

Authors:  L A Simons
Journal:  Am J Cardiol       Date:  1986-05-30       Impact factor: 2.778
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  4 in total

1.  Higher-order oligomerization of a chimeric αβγ bifunctional diterpene synthase with prenyltransferase and class II cyclase activities is concentration-dependent.

Authors:  Trey A Ronnebaum; Kushol Gupta; David W Christianson
Journal:  J Struct Biol       Date:  2020-01-21       Impact factor: 2.867

2.  In vitro and in vivo activities of E5700 and ER-119884, two novel orally active squalene synthase inhibitors, against Trypanosoma cruzi.

Authors:  Julio A Urbina; Juan Luis Concepcion; Aura Caldera; Gilberto Payares; Cristina Sanoja; Takeshi Otomo; Hironobu Hiyoshi
Journal:  Antimicrob Agents Chemother       Date:  2004-07       Impact factor: 5.191

Review 3.  Application of cyclic phosphonamide reagents in the total synthesis of natural products and biologically active molecules.

Authors:  Thilo Focken; Stephen Hanessian
Journal:  Beilstein J Org Chem       Date:  2014-08-13       Impact factor: 2.883

Review 4.  Human isoprenoid synthase enzymes as therapeutic targets.

Authors:  Jaeok Park; Alexios N Matralis; Albert M Berghuis; Youla S Tsantrizos
Journal:  Front Chem       Date:  2014-07-22       Impact factor: 5.221
  4 in total

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