Literature DB >> 12839470

Benzannulation of 3-substituted pyrroles to indoles.

Alan R Katritzky1, Stephane Ledoux, Satheesh K Nair.   

Abstract

In a new general indole synthesis, the anion derived from benzotriazolyl derivative 5b underwent regioselective 1,4-addition to various alpha,beta-unsaturated ketones; subsequent acid-catalyzed cyclization formed the corresponding indoles 1a-f.

Entities:  

Year:  2003        PMID： 12839470     DOI： 10.1021/jo026853m

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  3 in total

1.  Benzannulation via the reaction of ynamides and vinylketenes. application to the synthesis of highly substituted indoles.

Authors:  Tin Yiu Lam; Yu-Pu Wang; Rick L Danheiser
Journal:  J Org Chem       Date:  2013-09-03       Impact factor: 4.354

2.  Indole synthesis: a review and proposed classification.

Authors:  Douglass F Taber; Pavan K Tirunahari
Journal:  Tetrahedron       Date:  2011-09-23       Impact factor: 2.457

3.  A practical route to substituted 7-aminoindoles from pyrrole-3-carboxaldehydes.

Authors:  Victor K Outlaw; Craig A Townsend
Journal:  Org Lett       Date:  2014-12-05       Impact factor: 6.005
  3 in total

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