Literature DB >> 12838375

Novel bioreduction system for the production of chiral alcohols.

M Kataoka1, K Kita, M Wada, Y Yasohara, J Hasegawa, S Shimizu.   

Abstract

Chiral alcohols are useful intermediates for many pharmaceuticals and chemicals. Enzymatic asymmetric reduction of prochiral carbonyl compounds is a promising method for producing chiral alcohols. There have been many attempts to construct bioreduction systems for the industrial production of chiral alcohols. This review focuses on the establishment of a novel bioreduction system using an Escherichia coli transformant co-expressing genes for carbonyl reductase and cofactor-regeneration enzyme. This bioreduction system could be useful as an all-purpose catalyst for asymmetric reduction reactions.

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Year:  2003        PMID： 12838375     DOI： 10.1007/s00253-003-1347-y

Source DB:  PubMed          Journal:  Appl Microbiol Biotechnol        ISSN： 0175-7598            Impact factor:   4.813


  24 in total

1.  Synthesis of optically pure S-sulfoxide by Escherichia coli transformant cells coexpressing the P450 monooxygenase and glucose dehydrogenase genes.

Authors:  Jian-Dong Zhang; Ai-Tao Li; Hui-Lei Yu; Tadayuki Imanaka; Jian-He Xu
Journal:  J Ind Microbiol Biotechnol       Date:  2010-08-19       Impact factor: 3.346

2.  Efficient PCR-based amplification of diverse alcohol dehydrogenase genes from metagenomes for improving biocatalysis: screening of gene-specific amplicons from metagenomes.

Authors:  Nobuya Itoh; Satomi Kariya; Junji Kurokawa
Journal:  Appl Environ Microbiol       Date:  2014-08-01       Impact factor: 4.792

3.  Probing the substrate binding site of Candida tenuis xylose reductase (AKR2B5) with site-directed mutagenesis.

Authors:  Regina Kratzer; Stefan Leitgeb; David K Wilson; Bernd Nidetzky
Journal:  Biochem J       Date:  2006-01-01       Impact factor: 3.857

4.  The coenzyme specificity of Candida tenuis xylose reductase (AKR2B5) explored by site-directed mutagenesis and X-ray crystallography.

Authors:  Barbara Petschacher; Stefan Leitgeb; Kathryn L Kavanagh; David K Wilson; Bernd Nidetzky
Journal:  Biochem J       Date:  2005-01-01       Impact factor: 3.857

5.  Crystallization and preliminary X-ray analysis of the NADPH-dependent 3-quinuclidinone reductase from Rhodotorula rubra.

Authors:  Daijiro Takeshita; Michihiko Kataoka; Takuya Miyakawa; Ken-ichi Miyazono; Atsuko Uzura; Koji Nagata; Sakayu Shimizu; Masaru Tanokura
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2009-05-23

6.  Gene cloning and characterization of two NADH-dependent 3-quinuclidinone reductases from Microbacterium luteolum JCM 9174.

Authors:  Kentaro Isotani; Junji Kurokawa; Fumiko Suzuki; Syunsuke Nomoto; Takashi Negishi; Michiko Matsuda; Nobuya Itoh
Journal:  Appl Environ Microbiol       Date:  2012-12-21       Impact factor: 4.792

7.  Asymmetric reduction of 4-hydroxy-2-butanone to (R)-1,3-butanediol with absolute stereochemical selectivity by a newly isolated strain of Pichia jadinii.

Authors:  Taowei Yang; Zaiwei Man; Zhiming Rao; Meijuan Xu; Xian Zhang; Zhenghong Xu
Journal:  J Ind Microbiol Biotechnol       Date:  2014-10-12       Impact factor: 3.346

8.  Construction of microbial platform for an energy-requiring bioprocess: practical 2'-deoxyribonucleoside production involving a C-C coupling reaction with high energy substrates.

Authors:  Nobuyuki Horinouchi; Takafumi Sakai; Takako Kawano; Seiichiro Matsumoto; Mie Sasaki; Makoto Hibi; Jun Shima; Sakayu Shimizu; Jun Ogawa
Journal:  Microb Cell Fact       Date:  2012-06-15       Impact factor: 5.328

9.  Production of (R)-3-quinuclidinol by E. coli biocatalysts possessing NADH-dependent 3-quinuclidinone reductase (QNR or bacC) from Microbacterium luteolum and Leifsonia alcohol dehydrogenase (LSADH).

Authors:  Kentaro Isotani; Junji Kurokawa; Nobuya Itoh
Journal:  Int J Mol Sci       Date:  2012-10-19       Impact factor: 5.923

10.  Hydrogen-driven asymmetric reduction of hydroxyacetone to (R)-1,2-propanediol by Ralstonia eutropha transformant expressing alcohol dehydrogenase from Kluyveromyces lactis.

Authors:  Takahiro Oda; Koji Oda; Hiroaki Yamamoto; Akinobu Matsuyama; Masaharu Ishii; Yasuo Igarashi; Hirofumi Nishihara
Journal:  Microb Cell Fact       Date:  2013-01-10       Impact factor: 5.328
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