| Literature DB >> 12837359 |
H Sadraei1, A Ghannadi, K Malekshahi.
Abstract
The relaxant effect of the essential oil of Melissa officinalis and its main component, citral, on rat isolated ileum contractions was evaluated. M. officinalis essential oil (MOEO) inhibited the response to KCl (80 mM), ACh (320 nM) and 5-HT (1.28 microM) in a concentration-dependent manner with a IC(50) of approximately 20 ng/ml. Citral also had a concentration-dependent inhibitory effect on contraction of rat ileum with IC(50)s comparable to that of MOEO.Entities:
Mesh:
Substances:
Year: 2003 PMID: 12837359 DOI: 10.1016/s0367-326x(03)00109-6
Source DB: PubMed Journal: Fitoterapia ISSN: 0367-326X Impact factor: 2.882