Literature DB >> 12836806

A brief neuropsychological testing battery for evaluating patients with schizophrenia.

Robert M Savage1, Warren T Jackson, Choun M Sourathathone.   

Abstract

Current conceptualizations of schizophrenia include neurocognitive impairment, particularly in aspects of attention, memory, and executive functioning. Evaluation of these cognitive abilities typically involves use of comprehensive batteries which may take up to six hours to complete. The current study examined the effectiveness of a briefer battery to detect cognitive impairments usually seen in schizophrenia as established by previous studies using more lengthy and labor intensive protocols. The current study involved 61 outpatients with schizophrenia who were separated into three subgroups: paranoid type (n = 20), undifferentiated type (n = 21), and schizoaffective (n = 20). The majority of the patients were male (61%), African-American (52%), and of low socio-economic status. The mean age was 41.4 years (SD = 8.8), and the mean years of education was 11.7 (SD = 6.8). For the overall sample, results revealed mild to moderate impairments in memory, construction, concept formation, response set maintenance, psychomotor speed, and visual speed of information processing. Post-hoc analyses revealed significant differences between subgroups on Similarities and psychomotor speed, with the undifferentiated group performing more poorly than the paranoid or schizoaffective groups. In conclusion, the current brief battery minimized respondent burden in terms of both time demands and level of task complexity. However, it was also sensitive enough to capture many of the same cognitive weaknesses as those reported when using more labor-intensive neuropsychological test protocols.

Entities:  

Mesh:

Year:  2003        PMID: 12836806     DOI: 10.1023/a:1023394324161

Source DB:  PubMed          Journal:  Community Ment Health J        ISSN: 0010-3853


  23 in total

1.  Schizophrenia and the myth of intellectual decline.

Authors:  A J Russell; J C Munro; P B Jones; D R Hemsley; R M Murray
Journal:  Am J Psychiatry       Date:  1997-05       Impact factor: 18.112

2.  Lateralized brain dysfunction in schizophrenia: a comparison with patients with lateralized structural lesions.

Authors:  G Goldstein; D N Allen; C L Weiner
Journal:  Schizophr Res       Date:  1999-12-21       Impact factor: 4.939

3.  The Anomalous Sentences Repetition Test: replication and validation study.

Authors:  D J Weeks
Journal:  J Clin Psychol       Date:  1986-07

4.  Relative risk for cognitive impairments in siblings of patients with schizophrenia.

Authors:  M F Egan; T E Goldberg; T Gscheidle; M Weirich; R Rawlings; T M Hyde; L Bigelow; D R Weinberger
Journal:  Biol Psychiatry       Date:  2001-07-15       Impact factor: 13.382

5.  Spatial working memory deficits in schizophrenia: relationship with tardive dyskinesia and negative symptoms.

Authors:  C Pantelis; G W Stuart; H E Nelson; T W Robbins; T R Barnes
Journal:  Am J Psychiatry       Date:  2001-08       Impact factor: 18.112

6.  Stability and course of neuropsychological deficits in schizophrenia.

Authors:  R K Heaton; J A Gladsjo; B W Palmer; J Kuck; T D Marcotte; D V Jeste
Journal:  Arch Gen Psychiatry       Date:  2001-01

7.  Component analysis of verbal fluency in patients with schizophrenia.

Authors:  K K Zakzanis; A K Troyer; J B Rich; W Heinrichs
Journal:  Neuropsychiatry Neuropsychol Behav Neurol       Date:  2000-10

8.  Paired-associate learning and memory interference in schizophrenia.

Authors:  B Elvevåg; M F Egan; T E Goldberg
Journal:  Neuropsychologia       Date:  2000       Impact factor: 3.139

Review 9.  Should schizophrenia be treated as a neurocognitive disorder?

Authors:  M F Green; K H Nuechterlein
Journal:  Schizophr Bull       Date:  1999       Impact factor: 9.306

10.  Neurobehavioral and neurodiagnostic aspects of late-onset psychosis.

Authors:  C M Cullum; R K Heaton; M J Harris; D V Jeste
Journal:  Arch Clin Neuropsychol       Date:  1994-10       Impact factor: 2.813

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