Literature DB >> 12835706

Immunopathogenesis and immunotherapy in AIDS virus infections.

Norman L Letvin1, Bruce D Walker.   

Abstract

The heterogeneity of HIV and the different human leukocyte antigen (HLA) backgrounds of infected individuals have posed challenges to understanding the pathogenesis of HIV infection. But continuing advances in our knowledge of the role of immune responses in controlling HIV viremia should help to define goals for immune-based therapies and vaccine strategies against AIDS.

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Year:  2003        PMID： 12835706     DOI： 10.1038/nm0703-861

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


  95 in total

1.  Characterization of a thymus-tropic HIV-1 isolate from a rapid progressor: role of the envelope.

Authors:  Eric G Meissner; Karen M Duus; Feng Gao; Xiao-Fang Yu; Lishan Su
Journal:  Virology       Date:  2004-10-10       Impact factor: 3.616

2.  A Critical Role of IL-21-Induced BATF in Sustaining CD8-T-Cell-Mediated Chronic Viral Control.

Authors:  Gang Xin; David M Schauder; Begoña Lainez; Jason S Weinstein; Zhengxi Dai; Yuhong Chen; Enric Esplugues; Renren Wen; Demin Wang; Ian A Parish; Allan J Zajac; Joe Craft; Weiguo Cui
Journal:  Cell Rep       Date:  2015-10-29       Impact factor: 9.423

3.  Cell-intrinsic IL-27 and gp130 cytokine receptor signaling regulates virus-specific CD4⁺ T cell responses and viral control during chronic infection.

Authors:  James A Harker; Aleksandr Dolgoter; Elina I Zuniga
Journal:  Immunity       Date:  2013-08-29       Impact factor: 31.745

4.  In vivo targeting of dendritic cells for activation of cellular immunity using vaccine carriers based on pH-responsive microparticles.

Authors:  Young Jik Kwon; Edward James; Nilabh Shastri; Jean M J Fréchet
Journal:  Proc Natl Acad Sci U S A       Date:  2005-12-12       Impact factor: 11.205

5.  HIV-1 fusion peptide targets the TCR and inhibits antigen-specific T cell activation.

Authors:  Francisco J Quintana; Doron Gerber; Sally C Kent; Irun R Cohen; Yechiel Shai
Journal:  J Clin Invest       Date:  2005-07-07       Impact factor: 14.808

6.  Memory T cells in the chronic inflammatory microenvironment of nasal polyposis are hyporesponsive to signaling through the T cell receptor.

Authors:  Heather K Lehman; Michelle R Simpson-Abelson; Thomas F Conway; Raymond J Kelleher; Joel M Bernstein; Richard B Bankert
Journal:  J Assoc Res Otolaryngol       Date:  2012-02-04

7.  Exosomes Represent an Immune Suppressive T Cell Checkpoint in Human Chronic Inflammatory Microenvironments.

Authors:  Gautam N Shenoy; Maulasri Bhatta; Jenni L Loyall; Raymond J Kelleher; Joel M Bernstein; Richard B Bankert
Journal:  Immunol Invest       Date:  2020-04-17       Impact factor: 3.657

8.  Broad cross-clade T-cell responses to gag in individuals infected with human immunodeficiency virus type 1 non-B clades (A to G): importance of HLA anchor residue conservation.

Authors:  Mark J Geels; Sheri A Dubey; Kiersten Anderson; Elly Baan; Margreet Bakker; Georgios Pollakis; William A Paxton; John W Shiver; Jaap Goudsmit
Journal:  J Virol       Date:  2005-09       Impact factor: 5.103

Review 9.  Crosstalk between adaptive and innate immune cells leads to high quality immune protection at the mucosal borders.

Authors:  Hilde Cheroutre; Yujun Huang
Journal:  Adv Exp Med Biol       Date:  2013       Impact factor: 2.622

10.  TLR3 agonist and CD40-targeting vaccination induces immune responses and reduces HIV-1 reservoirs.

Authors:  Liang Cheng; Qi Wang; Guangming Li; Riddhima Banga; Jianping Ma; Haisheng Yu; Fumihiko Yasui; Zheng Zhang; Giuseppe Pantaleo; Matthieu Perreau; Sandra Zurawski; Gerard Zurawski; Yves Levy; Lishan Su
Journal:  J Clin Invest       Date:  2018-08-27       Impact factor: 14.808
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