Literature DB >> 12834443

Depression, stress and the adrenal axis.

Carmine M Pariante1.   

Abstract

Depression is characterized by an over activity of the hypothalamic-pituitary-adrenal (HPA) axis that resembles the neuroendocrine response to stress. These HPA axis abnormalities participate in the development of depressive symptoms. Moreover, antidepressants directly regulate HPA axis function. These novel findings are reshaping our understanding of the causes and treatment of this disabling disorder.

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Mesh：

Year:  2003        PMID： 12834443     DOI： 10.1046/j.1365-2826.2003.01058.x

Source DB:  PubMed          Journal:  J Neuroendocrinol        ISSN： 0953-8194            Impact factor:   3.627


  54 in total

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