Literature DB >> 12834001

Anti-inflammatory activity of shikonin derivatives from Arnebia hispidissima.

B Singh1, M K Sharma, P R Meghwal, P M Sahu, S Singh.   

Abstract

Arnebia hispidissima ethanolic extract, after chromatography, yielded a number of shikonin derivatives, which were identified as arnebin-5, arnebin-6, teracryl shikonin, arnebinone and acetyl shikonin. All these compounds were firstly reported from this plant species and evaluated to the anti-inflammatory activity of ethanolic extract and isolated shikonin derivatives, models with carrageenan-induced paw edema and complete Freund's adjuvant (CFA)-induced chronic arthritis in rats were conducted. The observed results indicated that pre-treatment with arnebinone significantly inhibited the carrageenan-induced paw edema and also suppressed the development of chronic arthritis induced by CFA.

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Year:  2003        PMID: 12834001     DOI: 10.1078/0944-7113-00262

Source DB:  PubMed          Journal:  Phytomedicine        ISSN: 0944-7113            Impact factor:   5.340


  10 in total

1.  Theoretical investigation of the radical scavenging activity of shikonin and acylshikonin derivatives.

Authors:  Ruifa Jin; Yin Bai
Journal:  J Mol Model       Date:  2011-07-15       Impact factor: 1.810

2.  Evaluation of the effectiveness of an ointment based on Alkannins/Shikonins on second intention wound healing in the dog.

Authors:  Maria Karayannopoulou; Vassiliki Tsioli; Panayiotis Loukopoulos; Tilemahos L Anagnostou; Nikolaos Giannakas; Ioannis Savvas; Lysimachos G Papazoglou; Eleni Kaldrymidou
Journal:  Can J Vet Res       Date:  2011-01       Impact factor: 1.310

3.  Polysaccharides from Arnebia euchroma Ameliorated Endotoxic Fever and Acute Lung Injury in Rats Through Inhibiting Complement System.

Authors:  Ying-Ye Ou; Yun Jiang; Hong Li; Yun-Yi Zhang; Yan Lu; Dao-Feng Chen
Journal:  Inflammation       Date:  2017-02       Impact factor: 4.092

4.  Dual role of shikonin in early and late stages of collagen type II arthritis.

Authors:  Qiaomei Dai; Jianghong Fang; Feng-shan Zhang
Journal:  Mol Biol Rep       Date:  2008-09-10       Impact factor: 2.316

5.  The anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis.

Authors:  Zeze Fu; Biyong Deng; Yuxin Liao; Liancheng Shan; Fei Yin; Zhuoying Wang; Hui Zeng; Dongqing Zuo; Yingqi Hua; Zhengdong Cai
Journal:  BMC Cancer       Date:  2013-12-06       Impact factor: 4.430

6.  Anti-inflammatory properties of shikonin contribute to improved early-stage diabetic retinopathy.

Authors:  Po-Lin Liao; Cheng-Hui Lin; Ching-Hao Li; Chi-Hao Tsai; Jau-Der Ho; George C Y Chiou; Jaw-Jou Kang; Yu-Wen Cheng
Journal:  Sci Rep       Date:  2017-03-21       Impact factor: 4.379

Review 7.  Review of Shikonin and Derivatives: Isolation, Chemistry, Biosynthesis, Pharmacology and Toxicology.

Authors:  Snehlata Yadav; Ajay Sharma; Gulzar Ahmad Nayik; Raymond Cooper; Garima Bhardwaj; Harvinder Singh Sohal; Vishal Mutreja; Ramandeep Kaur; Franklin Ore Areche; Mohannad AlOudat; Ayaz Mukarram Shaikh; Béla Kovács; Abdelhakam Esmaeil Mohamed Ahmed
Journal:  Front Pharmacol       Date:  2022-07-01       Impact factor: 5.988

8.  The Healing Effect of Arnebia Euchroma Ointment versus Silver Sulfadiazine on Burn Wounds in Rat.

Authors:  Ebrahim Nasiri; Seyed Jalal Hosseinimehr; Mohammad Azadbakht; Jafar Akbari; Reza Enayati-Fard; Sohail Azizi; Masoud Azadbakht
Journal:  World J Plast Surg       Date:  2015-07

9.  Toll-Like Receptor 4-Myeloid Differentiation Primary Response Gene 88 Pathway Is Involved in the Shikonin Treatment of CIA by Regulating Treg/Th17 Expression.

Authors:  Qiaomei Dai; Ji Li; Yu Yun; Jianwei Wang
Journal:  Evid Based Complement Alternat Med       Date:  2018-12-16       Impact factor: 2.629

10.  Antioxidant Potential and the Characterization of Arachis hypogaea Roots.

Authors:  Samee Ullah; Syed Ammar Hussain; Faryal Shaukat; Ahsan Hameed; Wu Yang; Yuanda Song
Journal:  Biomed Res Int       Date:  2019-12-20       Impact factor: 3.411

  10 in total

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