| Literature DB >> 12833063 |
Olga C Rodriguez1, Andrew W Schaefer, Craig A Mandato, Paul Forscher, William M Bement, Clare M Waterman-Storer.
Abstract
Interactions between microtubules and actin are a basic phenomenon that underlies many fundamental processes in which dynamic cellular asymmetries need to be established and maintained. These are processes as diverse as cell motility, neuronal pathfinding, cellular wound healing, cell division and cortical flow. Microtubules and actin exhibit two mechanistic classes of interactions--regulatory and structural. These interactions comprise at least three conserved 'mechanochemical activity modules' that perform similar roles in these diverse cell functions.Mesh：
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Year: 2003 PMID： 12833063 DOI： 10.1038/ncb0703-599
Source DB: PubMed Journal: Nat Cell Biol ISSN： 1465-7392 Impact factor: 28.824