| Literature DB >> 12831997 |
Tibor Wenger1, Gabriella Moldrich, Susanna Furst.
Abstract
The expression of central cannabinoid (CB1) receptors in tyrosine hydroxylase (TH) containing neurones was demonstrated. Co-localisation was present in different brain areas responsible for reward-related mechanisms. The immunohistochemical investigations have shown that co-localisation is present in parts of mesolimbic-mesocortical dopaminergic system like nucleus accumbens (Nacb), ventral tegmental area (VTA), in the striatum, pyriform cortex, respectively. The results suggest a functional role of CB1 receptors in cannabis addiction by acting directly on reward-related structures.Entities:
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Year: 2003 PMID: 12831997 DOI: 10.1016/s0361-9230(03)00081-9
Source DB: PubMed Journal: Brain Res Bull ISSN: 0361-9230 Impact factor: 4.077