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Literature DB >> 12831881

RNA folding: models and perspectives.

Abstract

Intrinsic events during RNA folding include conformational search and metal ion binding. Several experimentally testable models have been proposed to explain how large ribozymes accomplish folding. Future challenges include the validation of these models, and the correlation of experimental results and theoretical simulations.

Entities: Chemical

Mesh：

Substances：
RNA, Catalytic
RNA

Year: 2003 PMID： 12831881 DOI： 10.1016/s0959-440x(03)00066-6

Source DB: PubMed Journal: Curr Opin Struct Biol ISSN： 0959-440X Impact factor: 6.809

Keyword Cloud
Cited

56 in total

Review 1. Force as a useful variable in reactions: unfolding RNA.

Authors: Ignacio Tinoco
Journal: Annu Rev Biophys Biomol Struct Date: 2004

2. Freely diffusing single hairpin ribozymes provide insights into the role of secondary structure and partially folded states in RNA folding.

Authors: Goran Pljevaljcić; David P Millar; Ashok A Deniz
Journal: Biophys J Date: 2004-07 Impact factor: 4.033

3. Predicting ion binding properties for RNA tertiary structures.

Authors: Zhi-Jie Tan; Shi-Jie Chen
Journal: Biophys J Date: 2010-09-08 Impact factor: 4.033

4. Predicting secondary structural folding kinetics for nucleic acids.

Authors: Peinan Zhao; Wen-Bing Zhang; Shi-Jie Chen
Journal: Biophys J Date: 2010-04-21 Impact factor: 4.033

Review 5. Predicting and modeling RNA architecture.

Authors: Eric Westhof; Benoît Masquida; Fabrice Jossinet
Journal: Cold Spring Harb Perspect Biol Date: 2011-02-01 Impact factor: 10.005

Review 6. RNA folding in living cells.

Authors: Georgeta Zemora; Christina Waldsich
Journal: RNA Biol Date: 2010-11-01 Impact factor: 4.652

RNA folding: models and perspectives.

Review 1. Force as a useful variable in reactions: unfolding RNA.

2. Freely diffusing single hairpin ribozymes provide insights into the role of secondary structure and partially folded states in RNA folding.

3. Predicting ion binding properties for RNA tertiary structures.

4. Predicting secondary structural folding kinetics for nucleic acids.

Review 5. Predicting and modeling RNA architecture.

Review 6. RNA folding in living cells.

7. Fast formation of the P3-P7 pseudoknot: a strategy for efficient folding of the catalytically active ribozyme.

8. Exploring the complex folding kinetics of RNA hairpins: I. General folding kinetics analysis.

9. Structural basis for altering the stability of homologous RNAs from a mesophilic and a thermophilic bacterium.

10. Salt-dependent folding energy landscape of RNA three-way junction.