Literature DB >> 1283126

Serodiagnostic value of the 19 kilodalton antigen of Mycobacterium tuberculosis in Indian patients.

G Bothamley1, H Batra, V Ramesh, A Chandramui, J Ivanyi.   

Abstract

Previous studies in UK subjects suggested that the 19 kDa protein antigen of Mycobacterium tuberculosis might be valuable in the serodiagnosis of paucibacillary tuberculosis. In this study, antibody titres for the 19 kDa antigen were higher in healthy controls in India than in the UK. Consequently, the diagnostic sensitivity of this antigen and its TB23 epitope was negligible in Indian patients with tuberculosis. However, a diagnostic sensitivity of 50% was achieved in patients with skin tuberculosis on the basis of a high ratio between antibody titres for the whole antigen and its TB23 epitope.

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Year:  1992        PMID: 1283126     DOI: 10.1007/BF01962372

Source DB:  PubMed          Journal:  Eur J Clin Microbiol Infect Dis        ISSN: 0934-9723            Impact factor:   3.267


  12 in total

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Journal:  J Pediatr       Date:  1959-10       Impact factor: 4.406

Review 2.  The rapid diagnosis of tuberculosis: a selective review.

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Authors:  G Bothamley; P Udani; R Rudd; F Festenstein; J Ivanyi
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1988-10       Impact factor: 3.267

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Authors:  P S Jackett; G H Bothamley; H V Batra; A Mistry; D B Young; J Ivanyi
Journal:  J Clin Microbiol       Date:  1988-11       Impact factor: 5.948

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Journal:  Am Rev Respir Dis       Date:  1987-05

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Journal:  Tubercle       Date:  1974-12

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Journal:  J Clin Microbiol       Date:  1988-09       Impact factor: 5.948

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Journal:  Clin Exp Immunol       Date:  1984-12       Impact factor: 4.330

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Journal:  Scand J Immunol       Date:  1988-02       Impact factor: 3.487

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  11 in total

Review 1.  Clinical utility of serodiagnosis of tuberculosis.

Authors:  S Mahadevan
Journal:  Indian J Pediatr       Date:  1997 Jan-Feb       Impact factor: 1.967

Review 2.  Performance of purified antigens for serodiagnosis of pulmonary tuberculosis: a meta-analysis.

Authors:  Karen R Steingart; Nandini Dendukuri; Megan Henry; Ian Schiller; Payam Nahid; Philip C Hopewell; Andrew Ramsay; Madhukar Pai; Suman Laal
Journal:  Clin Vaccine Immunol       Date:  2008-12-03

3.  Immunoblot analysis for serodiagnosis of tuberculosis using a 45/47-kilodalton antigen complex of Mycobacterium tuberculosis.

Authors:  S Diagbouga; F Fumoux; A Zoubga; P T Sanou; G Marchal
Journal:  Clin Diagn Lab Immunol       Date:  1997-05

4.  Mycobacterium tuberculosis Des protein: an immunodominant target for the humoral response of tuberculous patients.

Authors:  M Jackson; D Portnoï; D Catheline; L Dumail; J Rauzier; P Legrand; B Gicquel
Journal:  Infect Immun       Date:  1997-07       Impact factor: 3.441

5.  Cloning and expression of immunoreactive antigens from Mycobacterium tuberculosis.

Authors:  R L Lim; L K Tan; W F Lau; M C Ming; R Dunn; H P Too; L Chan
Journal:  Clin Diagn Lab Immunol       Date:  2000-07

6.  Evaluation of an in-house-developed radioassay kit for antibody detection in cases of pulmonary tuberculosis and tuberculous meningitis.

Authors:  M Kameswaran; K Shetty; M K Ray; M A Jaleel; G V Kadival
Journal:  Clin Diagn Lab Immunol       Date:  2002-09

7.  Epitope-specific antibody levels demonstrate recognition of new epitopes and changes in titer but not affinity during treatment of tuberculosis.

Authors:  Graham H Bothamley
Journal:  Clin Diagn Lab Immunol       Date:  2004-09

8.  Epitope specificity and isoforms of the mycobacterial 19-kilodalton antigen.

Authors:  D P Harris; H M Vordermeier; S J Brett; G Pasvol; C Moreno; J Ivanyi
Journal:  Infect Immun       Date:  1994-07       Impact factor: 3.441

Review 9.  Function and Potentials of M. tuberculosis Epitopes.

Authors:  Juraj Ivanyi
Journal:  Front Immunol       Date:  2014-03-24       Impact factor: 7.561

10.  Effect of deletion or overexpression of the 19-kilodalton lipoprotein Rv3763 on the innate response to Mycobacterium tuberculosis.

Authors:  Graham R Stewart; Katalin A Wilkinson; Sandra M Newton; Susan M Sullivan; Olivier Neyrolles; John R Wain; Janisha Patel; Kara-Lee Pool; Douglas B Young; Robert J Wilkinson
Journal:  Infect Immun       Date:  2005-10       Impact factor: 3.441

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