Literature DB >> 12829250

PTP1B: from the sidelines to the front lines!

Nicholas K Tonks1.   

Abstract

Although initially viewed as housekeeping enzymes, research over the last 15 years has revealed that the protein tyrosine phosphatases (PTPs) are critical regulators of tyrosine phosphorylation-dependent signaling events and may represent novel targets for therapeutic intervention in a variety of human diseases. In this review I will describe some of the key advances in the characterization of the structure, regulation and function of the prototypic PTP, PTP1B, and illustrate how our understanding of the properties of this enzyme has revealed principles that apply to the PTP family as a whole.

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Year:  2003        PMID： 12829250     DOI： 10.1016/s0014-5793(03)00603-3

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  91 in total

1.  H2S-Induced sulfhydration of the phosphatase PTP1B and its role in the endoplasmic reticulum stress response.

Authors:  Navasona Krishnan; Cexiong Fu; Darryl J Pappin; Nicholas K Tonks
Journal:  Sci Signal       Date:  2011-12-13       Impact factor: 8.192

Review 2.  Transgenic mouse models resistant to diet-induced metabolic disease: is energy balance the key?

Authors:  Laura A A Gilliam; P Darrell Neufer
Journal:  J Pharmacol Exp Ther       Date:  2012-06-13       Impact factor: 4.030

3.  Protein tyrosine phosphatase 1B inhibitory activity of Indonesian herbal medicines and constituents of Cinnamomum burmannii and Zingiber aromaticum.

Authors:  Azis Saifudin; Shigetoshi Kadota; Yasuhiro Tezuka
Journal:  J Nat Med       Date:  2012-05-30       Impact factor: 2.343

4.  Protein tyrosine phosphatase-1B (PTP-1B) knockdown improves palmitate-induced insulin resistance in C2C12 skeletal muscle cells.

Authors:  Salar Bakhtiyari; Reza Meshkani; Mohammad Taghikhani; Bagher Larijani; Khosrow Adeli
Journal:  Lipids       Date:  2010-02-23       Impact factor: 1.880

5.  Interferon-γ alters downstream signaling originating from epidermal growth factor receptor in intestinal epithelial cells: functional consequences for ion transport.

Authors:  Gisela Paul; Ronald R Marchelletta; Declan F McCole; Kim E Barrett
Journal:  J Biol Chem       Date:  2011-11-08       Impact factor: 5.157

6.  Interaction with Grb14 results in site-specific regulation of tyrosine phosphorylation of the insulin receptor.

Authors:  Sébastien Nouaille; Christophe Blanquart; Vladimir Zilberfarb; Nicolas Boute; Dominique Perdereau; Johan Roix; Anne-Françoise Burnol; Tarik Issad
Journal:  EMBO Rep       Date:  2006-03-31       Impact factor: 8.807

7.  Role of protein tyrosine phosphatase 1B in vascular endothelial growth factor signaling and cell-cell adhesions in endothelial cells.

Authors:  Yoshimasa Nakamura; Nikolay Patrushev; Hyoe Inomata; Dolly Mehta; Norifumi Urao; Ha Won Kim; Masooma Razvi; Vidisha Kini; Kalyankar Mahadev; Barry J Goldstein; Ronald McKinney; Tohru Fukai; Masuko Ushio-Fukai
Journal:  Circ Res       Date:  2008-05-01       Impact factor: 17.367

8.  Regulation of the Met receptor-tyrosine kinase by the protein-tyrosine phosphatase 1B and T-cell phosphatase.

Authors:  Veena Sangwan; Grigorios N Paliouras; Jasmine V Abella; Nadia Dubé; Anie Monast; Michel L Tremblay; Morag Park
Journal:  J Biol Chem       Date:  2008-09-26       Impact factor: 5.157

9.  Resveratrol inhibits PDGF receptor mitogenic signaling in mesangial cells: role of PTP1B.

Authors:  Balachandar Venkatesan; Nandini Ghosh-Choudhury; Falguni Das; Lenin Mahimainathan; Amrita Kamat; Balakuntalam S Kasinath; Hanna E Abboud; Goutam Ghosh Choudhury
Journal:  FASEB J       Date:  2008-06-20       Impact factor: 5.191

10.  Protein tyrosine phosphatase interacting protein 51 (PTPIP51) mRNA expression and localization and its in vitro interacting partner protein tyrosine phosphatase 1B (PTP1B) in human placenta of the first, second, and third trimester.

Authors:  Albrecht Stenzinger; David Märker; Philipp Koch; Jens Hoffmann; Nelli Baal; Klaus Steger; Monika Wimmer
Journal:  J Histochem Cytochem       Date:  2008-10-14       Impact factor: 2.479
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