| Literature DB >> 12829240 |
An Rykx1, Line De Kimpe, Svetlana Mikhalap, Tibor Vantus, Thomas Seufferlein, Jackie R Vandenheede, Johan Van Lint.
Abstract
The protein kinase D family of enzymes consists of three isoforms: PKD1/PKCmu PKD2 and PKD3/PKCnu. They all share a similar architecture with regulatory sub-domains that play specific roles in the activation, translocation and function of the enzymes. The PKD enzymes have recently been implicated in very diverse cellular functions, including Golgi organization and plasma membrane directed transport, metastasis, immune responses, apoptosis and cell proliferation.Entities:
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Year: 2003 PMID： 12829240 DOI： 10.1016/s0014-5793(03)00487-3
Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124