Literature DB >> 128286

Severe alcoholic cardiomyopathy reversed with abstention from alcohol.

L Schwartz, K A Sample, D E Wigle.   

Abstract

In a chronic alcoholic with a severe congestive cardiomyopathy the angiographic and hemodynamic evidence of left ventricular dysfunction was completely reversed after 1 year of abstinence. At the time of initial presentation two of the traditional hallmarks of a poor prognosis were present, namely, a long exposure to alcohol before the onset of symptoms and severe diffuse left ventricular dilation and hypokinesis (ejection fraction 14.9 percent). Yet, today, 18 months later he is asymptomatic, receiving no medications and has normal left ventricular function. A reexamination of prognostic factors in alcoholic cardiomyopathy may be indicated.

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Year:  1975        PMID: 128286     DOI: 10.1016/0002-9149(75)90090-9

Source DB:  PubMed          Journal:  Am J Cardiol        ISSN: 0002-9149            Impact factor:   2.778


  9 in total

1.  Abstention from alcohol in dilated cardiomyopathy: complete regression of the clinical disease but persistence of myocardial perfusion defects on exercise thallium-201 tomography.

Authors:  Y Juillière; C Gillet; N Danchin; A Thouvenin; G Karcher; F Paille; A Bertrand; D Barrucand; F Cherrier
Journal:  Eur J Nucl Med       Date:  1990

Review 2.  Cardiovascular effects of alcohol.

Authors:  D M Davidson
Journal:  West J Med       Date:  1989-10

Review 3.  Congestive heart failure arising from diastolic dysfunction in the presence of normal left-ventricular systolic function.

Authors:  R F Stainback
Journal:  Tex Heart Inst J       Date:  1999

4.  Ultrastructural morphometric study on the rat heart after chronic ethanol feeding.

Authors:  G Mall; T Mattfeldt; B Volk
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1980

5.  Reversibility of alcoholic cardiomyopathy.

Authors:  M Kupari
Journal:  Postgrad Med J       Date:  1984-02       Impact factor: 2.401

6.  The effect of abstinence on left ventricular performance in asymptomatic chronic alcoholics.

Authors:  R Slutsky; F Berger; P Garver
Journal:  Cardiovasc Intervent Radiol       Date:  1983       Impact factor: 2.740

7.  Nonoxidative ethanol metabolism: formation of fatty acid ethyl esters by cholesterol esterase.

Authors:  L G Lange
Journal:  Proc Natl Acad Sci U S A       Date:  1982-07       Impact factor: 11.205

Review 8.  Cardiac abnormalities in liver cirrhosis.

Authors:  S S Lee
Journal:  West J Med       Date:  1989-11

9.  Mitochondrial dysfunction induced by fatty acid ethyl esters, myocardial metabolites of ethanol.

Authors:  L G Lange; B E Sobel
Journal:  J Clin Invest       Date:  1983-08       Impact factor: 14.808

  9 in total

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