| Literature DB >> 12827505 |
Armin Merckelbach1, Martina Wager, Richard Lucius.
Abstract
A cDNA library based on mRNA from oncospheres of Echinococcus multilocularis was constructed and screened with an oncosphere-specific rabbit serum. cDNA sequences of three clones that were isolated out of this library are discussed: one codes for a serpin-like proteinase inhibitor, the first isolated from cestodes. Two other clones code for dominant oncosphere antigens and represent homologues of known genes: one is known from several taeniid cestodes as a protective antigen containing fibronectin III domains, the second is related to genes of small heat shock proteins. It contains an internal duplication that might be specific for platyhelminths.Entities:
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Year: 2003 PMID: 12827505 DOI: 10.1007/s00436-003-0888-4
Source DB: PubMed Journal: Parasitol Res ISSN: 0932-0113 Impact factor: 2.289