Literature DB >> 1282730

In vitro transmission and antigenicity of a retrovirus isolated from a multiple sclerosis patient.

H Perron1, B Gratacap, B Lalande, O Genoulaz, A Laurent, C Geny, M Mallaret, P Innocenti, E Schuller, P Stoebner.   

Abstract

We have recently isolated an apparently novel retrovirus (LM7) from a patient with multiple sclerosis (MS). We present here results showing that (1) LM7 retrovirus can be transmitted in vitro to a normal human leptomeningeal cell culture and that (2) specific antibody against this retroviral strain can be detected in MS cases. Our results suggest that, if this virus is an endogenous retrovirus, it is different from human endogenous elements already described.

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Year:  1992        PMID： 1282730     DOI： 10.1016/s0923-2516(06)80122-6

Source DB:  PubMed          Journal:  Res Virol        ISSN： 0923-2516


  10 in total

1.  Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis. The Collaborative Research Group on Multiple Sclerosis.

Authors:  H Perron; J A Garson; F Bedin; F Beseme; G Paranhos-Baccala; F Komurian-Pradel; F Mallet; P W Tuke; C Voisset; J L Blond; B Lalande; J M Seigneurin; B Mandrand
Journal:  Proc Natl Acad Sci U S A       Date:  1997-07-08       Impact factor: 11.205

2.  Reduced expression of human endogenous retrovirus (HERV)-W GAG protein in the cingulate gyrus and hippocampus in schizophrenia, bipolar disorder, and depression.

Authors:  S Weis; I C Llenos; S Sabunciyan; J R Dulay; L Isler; R Yolken; H Perron
Journal:  J Neural Transm (Vienna)       Date:  2007-01-15       Impact factor: 3.575

3.  Human endogenous retrovirus (HERV)-W ENV and GAG proteins: physiological expression in human brain and pathophysiological modulation in multiple sclerosis lesions.

Authors:  Hervé Perron; Françoise Lazarini; Klemens Ruprecht; Christine Péchoux-Longin; Danielle Seilhean; Véronique Sazdovitch; Alain Créange; Nicole Battail-Poirot; Geneviève Sibaï; Lyse Santoro; Michel Jolivet; Jean-Luc Darlix; Peter Rieckmann; Thomas Arzberger; Jean-Jacques Hauw; Hans Lassmann
Journal:  J Neurovirol       Date:  2005-02       Impact factor: 2.643

4.  Molecular characterization and placental expression of HERV-W, a new human endogenous retrovirus family.

Authors:  J L Blond; F Besème; L Duret; O Bouton; F Bedin; H Perron; B Mandrand; F Mallet
Journal:  J Virol       Date:  1999-02       Impact factor: 5.103

Review 5.  The human endogenous retrovirus link between genes and environment in multiple sclerosis and in multifactorial diseases associating neuroinflammation.

Authors:  Hervé Perron; Alois Lang
Journal:  Clin Rev Allergy Immunol       Date:  2010-08       Impact factor: 8.667

Review 6.  Human endogenous retroviruses and the nervous system.

Authors:  Renée N Douville; Avindra Nath
Journal:  Handb Clin Neurol       Date:  2014

Review 7.  The multiple sclerosis-associated retrovirus and its HERV-W endogenous family: a biological interface between virology, genetics, and immunology in human physiology and disease.

Authors:  Antonina Dolei; Hervé Perron
Journal:  J Neurovirol       Date:  2008-11-26       Impact factor: 2.643

Review 8.  Viruses and multiple sclerosis.

Authors:  Jussi Oskari Virtanen; Steve Jacobson
Journal:  CNS Neurol Disord Drug Targets       Date:  2012-08       Impact factor: 4.388

Review 9.  HSV-1 and Endogenous Retroviruses as Risk Factors in Demyelination.

Authors:  Raquel Bello-Morales; Sabina Andreu; Inés Ripa; José Antonio López-Guerrero
Journal:  Int J Mol Sci       Date:  2021-05-27       Impact factor: 5.923

Review 10.  Human RNA "rumor" viruses: the search for novel human retroviruses in chronic disease.

Authors:  Cécile Voisset; Robin A Weiss; David J Griffiths
Journal:  Microbiol Mol Biol Rev       Date:  2008-03       Impact factor: 13.044
  10 in total

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