UNLABELLED: With this study we try to find out the interaction of sulpiride in tinnitus pathology. This, could help us to control better the tinnitus through tinnitus retraining therapy. MATERIAL AND METHODS:A hundred patients with tinnitus were divided into two groups of 50. Fifty milligrams of sulpiride or placebo were administered for three months, three time per day, with monthly controls. Clinical response, audiometry, tympanometry and acufenometry were registered. RESULTS: In the first month of treatment, only 58% of patients treated with sulpiride improved, and 17% of those treated with placebo, with statistical significance. In the second month, 41% and 20% respectively, and in the third month, 42% and 17% respectively. CONCLUSION: In patients with tinnitus, treatment with sulpiride has improved more than half of them in the first month of treatment. This time is crucial to begin tinnitus retraining therapy and to obtain a greater efficacy.
RCT Entities:
UNLABELLED: With this study we try to find out the interaction of sulpiride in tinnitus pathology. This, could help us to control better the tinnitus through tinnitus retraining therapy. MATERIAL AND METHODS: A hundred patients with tinnitus were divided into two groups of 50. Fifty milligrams of sulpiride or placebo were administered for three months, three time per day, with monthly controls. Clinical response, audiometry, tympanometry and acufenometry were registered. RESULTS: In the first month of treatment, only 58% of patients treated with sulpiride improved, and 17% of those treated with placebo, with statistical significance. In the second month, 41% and 20% respectively, and in the third month, 42% and 17% respectively. CONCLUSION: In patients with tinnitus, treatment with sulpiride has improved more than half of them in the first month of treatment. This time is crucial to begin tinnitus retraining therapy and to obtain a greater efficacy.
Authors: Ektor Tsuneo Onishi; Cláudia Couto de Barros Coelho; Jeanne Oiticica; Ricardo Rodrigues Figueiredo; Rita de Cassia Cassou Guimarães; Tanit Ganz Sanchez; Adriana Lima Gürtler; Alessandra Ramos Venosa; André Luiz Lopes Sampaio; Andreia Aparecida Azevedo; Anna Paula Batista de Ávila Pires; Bruno Borges de Carvalho Barros; Carlos Augusto Costa Pires de Oliveira; Clarice Saba; Fernando Kaoru Yonamine; Ítalo Roberto Torres de Medeiros; Letícia Petersen Schmidt Rosito; Marcelo José Abras Rates; Márcia Akemi Kii; Mariana Lopes Fávero; Mônica Alcantara de Oliveira Santos; Osmar Clayton Person; Patrícia Ciminelli; Renata de Almeida Marcondes; Ronaldo Kennedy de Paula Moreira; Sandro de Menezes Santos Torres Journal: Braz J Otorhinolaryngol Date: 2017-12-24