Literature DB >> 1282320

Detection of retinoic acid receptor mRNA in rat tissues by reverse transcriptase-polymerase chain reaction.

Y J Wan1, L Wang, T C Wu.   

Abstract

The presence of retinoic acid receptor (RAR) alpha, beta and gamma mRNA was examined in 16 different kinds of rat tissue using the highly sensitive reverse transcriptase-polymerase chain reaction technique. The data demonstrated that each tissue expressed at least two types of RAR mRNA. Among the three types of RAR mRNA, RAR alpha was widely expressed in all types of organ and was the dominant form expressed in the gastrointestinal tract. RAR beta mRNA was not present in the intestine and spleen. In addition, RAR beta mRNA levels were high in the heart, lung, brain, testis and epididymis. RAR gamma mRNA was abundant in both male and female reproductive systems, as well as epidermal tissues. The prevalence of each RAR mRNA in the tissues suggests the diverse biological roles of these receptors.

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Year:  1992        PMID： 1282320     DOI： 10.1677/jme.0.0090291

Source DB:  PubMed          Journal:  J Mol Endocrinol        ISSN： 0952-5041            Impact factor:   5.098


  6 in total

1.  Protein and ligand adaptation in a retinoic acid binding protein.

Authors:  R Pattanayek; M E Newcomer
Journal:  Protein Sci       Date:  1999-10       Impact factor: 6.725

2.  Effects of all-trans-retinoic acid (atRA) on inducible nitric oxide synthase (iNOS) activity and transforming growth factor beta-1 production in experimental anti-GBM antibody-mediated glomerulonephritis.

Authors:  P K Datta; R S Reddy; E A Lianos
Journal:  Inflammation       Date:  2001-12       Impact factor: 4.092

3.  Inhibition of nitric oxide synthesis in vascular smooth muscle by retinoids.

Authors:  K Hirokawa; K M O'Shaughnessy; P Ramrakha; M R Wilkins
Journal:  Br J Pharmacol       Date:  1994-12       Impact factor: 8.739

4.  Retinoic acid receptor signaling is necessary in steroidogenic cells for normal spermatogenesis and epididymal function.

Authors:  Estela J Jauregui; Debra Mitchell; Traci Topping; Cathryn A Hogarth; Michael D Griswold
Journal:  Development       Date:  2018-07-09       Impact factor: 6.868

5.  Gene expression of retinoic acid receptors and cellular retinoic acid-binding proteins in rhino and hairless mouse skin.

Authors:  B C Beehler; S Chen; K M Tramposch
Journal:  Arch Dermatol Res       Date:  1995       Impact factor: 3.017

6.  Activation of Akt pathway by transcription-independent mechanisms of retinoic acid promotes survival and invasion in lung cancer cells.

Authors:  Alejandro García-Regalado; Miguel Vargas; Alejandro García-Carrancá; Elena Aréchaga-Ocampo; Claudia Haydée González-De la Rosa
Journal:  Mol Cancer       Date:  2013-05-21       Impact factor: 27.401
  6 in total

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