E Ernst1. 1. Complementary Medicine, Peninsula Medical School, Universities of Exeter & Plymouth, Exeter, UK. edzard.ernst@pms.ac.uk
Abstract
OBJECTIVE: Psychiatric and neurological patients frequently try herbal medicines often under the assumption that they are safe. The aim of this systematic review was to provide a summary of recent data on severe psychiatric and neurological adverse effects of herbal remedies. METHOD: Computerized literature searches were carried out to identify all reports of psychiatric and neurological adverse effects associated with herbal medicines. These data were subsequently extracted, validated and summarized in narrative and tabular form. RESULTS: Numerous case reports comprise a diverse array of adverse events including cerebral arteritis, cerebral oedema, delirium, coma, confusion, encephalopathy, hallucinations, intracerebral haemorrhage, and other types of cerebrovascular accidents, movement disorders, mood disturbances, muscle weakness, paresthesiae and seizures. Several fatalities are on record. They are caused by improper use, toxicity of herbal ingredients, contamination and adulteration of preparations and herb/drug interactions. CONCLUSION: Herbal medicines can cause serious psychiatric and neurological adverse effects.
OBJECTIVE:Psychiatric and neurological patients frequently try herbal medicines often under the assumption that they are safe. The aim of this systematic review was to provide a summary of recent data on severe psychiatric and neurological adverse effects of herbal remedies. METHOD: Computerized literature searches were carried out to identify all reports of psychiatric and neurological adverse effects associated with herbal medicines. These data were subsequently extracted, validated and summarized in narrative and tabular form. RESULTS: Numerous case reports comprise a diverse array of adverse events including cerebral arteritis, cerebral oedema, delirium, coma, confusion, encephalopathy, hallucinations, intracerebral haemorrhage, and other types of cerebrovascular accidents, movement disorders, mood disturbances, muscle weakness, paresthesiae and seizures. Several fatalities are on record. They are caused by improper use, toxicity of herbal ingredients, contamination and adulteration of preparations and herb/drug interactions. CONCLUSION: Herbal medicines can cause serious psychiatric and neurological adverse effects.
Authors: Michael Bauer; Tasha Glenn; Jörn Conell; Natalie Rasgon; Wendy Marsh; Kemal Sagduyu; Rodrigo Munoz; Ute Lewitzka; Rita Bauer; Maximilian Pilhatsch; Scott Monteith; Peter C Whybrow Journal: Int J Bipolar Disord Date: 2015-06-02
Authors: Andrew Stickley; Ai Koyanagi; Erica Richardson; Bayard Roberts; Dina Balabanova; Martin McKee Journal: BMC Complement Altern Med Date: 2013-04-11 Impact factor: 3.659