Literature DB >> 12823109

IVIG--mechanisms of action.

H U Simon1, P J Späth.   

Abstract

Intravenous immunoglobulin (IVIG) preparations are fractionated from a plasma pool of several thousand donors. IVIG contain immune antibodies and physiologic autoantibodies. Immune antibodies reflect the immunologic experience of the donor population. This fraction of IVIG preparations is useful for replacement therapy and passive immunisation. Natural autoantibodies are able to react with the immune system of the recipient of IVIG and are suggested to help to correct immune deregulation. Immunomodulatory and anti-inflammatory properties are based on multiple mechanisms of action which are described. These mechanisms are effective concomitantly and synergistically at every occasion of use of IVIG in inflammatory and autoimmune disorders.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12823109     DOI： 10.1034/j.1398-9995.2003.00239.x

Source DB:  PubMed          Journal:  Allergy        ISSN： 0105-4538            Impact factor:   13.146


  19 in total

Review 1.  Intravenous immunoglobulin and recurrent pregnancy loss.

Authors:  Howard J A Carp; Tal Sapir; Yehuda Shoenfeld
Journal:  Clin Rev Allergy Immunol       Date:  2005-12       Impact factor: 8.667

2.  Privigen immune globulin intravenous (human), 10% liquid.

Authors: 
Journal:  P T       Date:  2011-08

Review 3.  Natural antibodies, intravenous immunoglobulin and their role in autoimmunity, cancer and inflammation.

Authors:  R Schwartz-Albiez; R C Monteiro; M Rodriguez; C J Binder; Y Shoenfeld
Journal:  Clin Exp Immunol       Date:  2009-12       Impact factor: 4.330

4.  Dyshidrotic eczema associated with the use of IVIg.

Authors:  Dilcan Kotan; Teoman Erdem; Bilgehan Atilgan Acar; Ayhan Boluk
Journal:  BMJ Case Rep       Date:  2013-02-15

Review 5.  Use of intravenous immunoglobulin in pediatric practice.

Authors:  Bülent Zülfikar; Başak Koç
Journal:  Turk Pediatri Ars       Date:  2014-12-01

Review 6.  Is intravenous immunoglobulins (IVIG) efficacious in early pregnancy failure? A critical review and meta-analysis for patients who fail in vitro fertilization and embryo transfer (IVF).

Authors:  David A Clark; Carolyn B Coulam; Raphael B Stricker
Journal:  J Assist Reprod Genet       Date:  2006-01-19       Impact factor: 3.412

Review 7.  Update on treatment and preventive interventions against COVID-19: an overview of potential pharmacological agents and vaccines.

Authors:  Yinan Xiao; Hanyue Xu; Wen Guo; Yunuo Zhao; Yuling Luo; Ming Wang; Zhiyao He; Zhenyu Ding; Jiyan Liu; Lei Deng; Fushen Sha; Xuelei Ma
Journal:  Mol Biomed       Date:  2020-12-03

Review 8.  Post-exposure passive immunisation for preventing rubella and congenital rubella syndrome.

Authors:  Megan K Young; Allan W Cripps; Graeme R Nimmo; Mieke L van Driel
Journal:  Cochrane Database Syst Rev       Date:  2015-09-09

9.  Heterosubtypic anti-avian H5N1 influenza antibodies in intravenous immunoglobulins from globally separate populations protect against H5N1 infection in cell culture.

Authors:  John S Sullivan; Paul W Selleck; Teena Downton; Ingrid Boehm; Anna-Maree Axell; Yasmin Ayob; Natalie M Kapitza; Wayne Dyer; Anna Fitzgerald; Bradley Walsh; Garry W Lynch
Journal:  J Mol Genet Med       Date:  2009-12-23

10.  Opsonization of malaria-infected erythrocytes activates the inflammasome and enhances inflammatory cytokine secretion by human macrophages.

Authors:  Jingling Zhou; Louise E Ludlow; Wina Hasang; Stephen J Rogerson; Anthony Jaworowski
Journal:  Malar J       Date:  2012-10-09       Impact factor: 2.979
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.