| Literature DB >> 12820955 |
Abstract
Emi1 inhibits the anaphase-promoting complex (APC) during S and G2 phase. Two papers by Guardavaccaro et al. and Margottin-Goguet et al. in the June issue of Developmental Cell now show that Emi1 degradation in early mitosis is mediated by beta-Trcp1, an adaptor protein that recruits proteins to the SCF ubiquitin ligase.Entities:
Mesh：
Substances：
Year: 2003 PMID： 12820955 DOI： 10.1016/s1097-2765(03)00233-8
Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 17.970