Literature DB >> 12820590

Acute colon diverticulitis in multiple myeloma patient: an unusual presentation of a colonic perforation. Case report.

G Soliani1, M Dominici, L Bergossi, E Basaglia, S Pauli, P Carcoforo.   

Abstract

This case report describes an acute colonic diverticular perforation occurred to a multiple myeloma patient, taking corticosteroid and morphine therapy, revealed by a subcutaneous emphysema of upper chest and right abdomen as initial presentation. Sigmoid diverticulitis with perforation and generalized peritonitis is a severe complication of the diverticular disease and it is due to diverticular microperforation. This condition occurs more frequently in patients with widespread diverticolosis and usually after 50 years of age, and the frequency of related complications increases with age (and with the use of corticosteroids). Extraperitoneal air from the sigmoid-rectum perforation can escape diffusing superiorly though paravertebral retroperitoneal tissues and via the diaphragmatic iatus into the mediastinum, producing pneumomediastinum and it diffuses to yield superior thoracic emphysema. This report suggests that the diagnosis of retroperitoneal perforation is usually difficult because of the lack of signs of peritoneal irritation and the paucity of symptoms, particularly in patients treated with corticosteroids.

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Year:  2002        PMID: 12820590

Source DB:  PubMed          Journal:  Ann Ital Chir        ISSN: 0003-469X            Impact factor:   0.766


  5 in total

1.  Pneumomediastinum as a presenting symptom of perforated sigmoid cancer: a case report.

Authors:  Raymond Farah; Nicola Makhoul
Journal:  Cases J       Date:  2009-06-09

Review 2.  Medical influences, surgical outcomes: role of common medications on the risk of perforation from untreated diverticular disease.

Authors:  Gianpiero Gravante; Shuker Yahia
Journal:  World J Gastroenterol       Date:  2013-09-28       Impact factor: 5.742

3.  Subcutaneous cervical emphysema and pneumomediastinum due to a diastatic rupture of the cecum.

Authors:  R Vecchio; E Intagliata; F Basile; C Spataro; G Giulia; V Leanza; S Marchese
Journal:  G Chir       Date:  2015 Nov-Dec

4.  Acute diverticulitis masquerading as unilateral sciatica-like symptoms.

Authors:  Victoria Novoselova; Alexandre Lacasse
Journal:  J Community Hosp Intern Med Perspect       Date:  2020-10-29

5.  Colon perforation in multiple myeloma patients - A complication of high-dose steroid treatment.

Authors:  Iuliana Vaxman; Abdullah S Al Saleh; Shaji Kumar; Mishra Nitin; Angela Dispenzieri; Francis Buadi; David Dingli; Martha Lacy; Eli Muchtar; Miriam Hobbs; Amie Fonder; Lisa Hwa; Alissa Visram; Prashant Kapoor; Mustaqeem Siddiqui; John Lust; Robert Kyle; Vincent Rajkumar; Suzanne Hayman; Nelson Leung; Wilson Gonsalves; Taxiarchis Kourelis; Rahma Warsame; Morie A Gertz
Journal:  Cancer Med       Date:  2020-10-06       Impact factor: 4.452

  5 in total

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