Literature DB >> 12818426

Identification of a glucocorticoid response element in the 3'-flanking region of the human Dexras1 gene.

Robert J Kemppainen1, Elaine Cox, Ellen N Behrend, Michele D Brogan, Jessica M Ammons.   

Abstract

The Dexras1 gene responds to glucocorticoids with a rapid and profound induction. A glucocorticoid response element (GRE) was identified in the 3'-flanking region (2.3 kb downstream of poly(A) signal) of the human Dexras1 gene. This element conferred rapid glucocorticoid responsiveness when inserted into a homologous promoter-driven luciferase reporter. A point mutation within the 15-bp GRE abolished this glucocorticoid responsiveness.

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Year:  2003        PMID： 12818426     DOI： 10.1016/s0167-4781(03)00079-4

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  11 in total

1.  Intronic hormone response elements mediate regulation of FKBP5 by progestins and glucocorticoids.

Authors:  Tina R Hubler; Jonathan G Scammell
Journal:  Cell Stress Chaperones       Date:  2004       Impact factor: 3.667

2.  Amphetamine up-regulates activator of G-protein signaling 1 mRNA and protein levels in rat frontal cortex: the role of dopamine and glucocorticoid receptors.

Authors:  M Schwendt; J F McGinty
Journal:  Neuroscience       Date:  2010-03-15       Impact factor: 3.590

Review 3.  Activators of G protein signaling in the kidney.

Authors:  Frank Park
Journal:  J Pharmacol Exp Ther       Date:  2015-01-27       Impact factor: 4.030

Review 4.  Mechanistic pathways and biological roles for receptor-independent activators of G-protein signaling.

Authors:  Joe B Blumer; Alan V Smrcka; Stephen M Lanier
Journal:  Pharmacol Ther       Date:  2006-11-28       Impact factor: 12.310

5.  Localization and expression profile of Group I and II Activators of G-protein Signaling in the kidney.

Authors:  Marek Lenarczyk; Jeffrey D Pressly; Joanna Arnett; Kevin R Regner; Frank Park
Journal:  J Mol Histol       Date:  2014-12-23       Impact factor: 2.611

6.  Dex-ras1 and serum- and glucocorticoid-inducible protein kinase 1: regulation of expression by dexamethasone in HEK293 cells.

Authors:  Ghassem Attarzadeh-Yazdi; Michael J Shipston; Ferenc A Antoni
Journal:  Neurochem Res       Date:  2007-11-06       Impact factor: 3.996

Review 7.  The Roles of Rasd1 small G proteins and leptin in the activation of TRPC4 transient receptor potential channels.

Authors:  Jinhong Wie; Byung Joo Kim; Jongyun Myeong; Kotdaji Ha; Seung Joo Jeong; Dongki Yang; Euiyong Kim; Ju-Hong Jeon; Insuk So
Journal:  Channels (Austin)       Date:  2015-06-17       Impact factor: 2.581

Review 8.  Accessory proteins for heterotrimeric G-proteins in the kidney.

Authors:  Frank Park
Journal:  Front Physiol       Date:  2015-08-07       Impact factor: 4.566

Review 9.  Small G Proteins Dexras1 and RHES and Their Role in Pathophysiological Processes.

Authors:  Ashish Thapliyal; Rashmi Verma; Navin Kumar
Journal:  Int J Cell Biol       Date:  2014-03-20

10.  Rasd1, a small G protein with a big role in the hypothalamic response to neuronal activation.

Authors:  Michael P Greenwood; Mingkwan Greenwood; Andre S Mecawi; José Antunes-Rodrigues; Julian F R Paton; David Murphy
Journal:  Mol Brain       Date:  2016-01-07       Impact factor: 4.041
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