| Literature DB >> 12818346 |
Anthony G Robson1, Jack D Moreland, Daniel Pauleikhoff, Tony Morrissey, Graham E Holder, Fred W Fitzke, Alan C Bird, Frederik J G M van Kuijk.
Abstract
Macular pigment (MP) distribution profiles were measured for 18 subjects using a Moreland anomaloscope modified for motion photometry. The total amount of MP within the central 7 degrees was estimated from the distribution profile by numerical integration. Fundus autofluorescence images were obtained for eight of these subjects using a scanning laser ophthalmoscope. Peak optical density of MP increased with the total amount present, but the correlation was weakened by inter-subject differences in MP distribution. The mean MP distribution derived from mean grey-scale profiles of fundus autofluorescence images correlated closely with that obtained psychophysically (r=0.96). Autofluorescence imaging provides a fast non-invasive method for assessing MP in vivo.Mesh:
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Year: 2003 PMID: 12818346 DOI: 10.1016/s0042-6989(03)00280-3
Source DB: PubMed Journal: Vision Res ISSN: 0042-6989 Impact factor: 1.886