Literature DB >> 1281638

B-cell tolerance.

C C Goodnow1.   

Abstract

Discrimination between self and non-self in humoral immunity is mediated in part by elimination or inactivation of self-reactive B-cell clones. This type of repertoire censoring requires that self-reactive B cells make a choice between these and alternative cellular fates. The details of this developmental decision-making and the steps where it is prone to go awry in autoimmunity have yet to be untangled, but genetic analysis appears likely to lead the way.

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Year:  1992        PMID： 1281638     DOI： 10.1016/0952-7915(92)90049-k

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  6 in total

1.  The immunogenicity of antibody aggregates in a novel transgenic mouse model.

Authors:  Juliana Bessa; Sabine Boeckle; Hermann Beck; Thomas Buckel; Sonja Schlicht; Martin Ebeling; Anna Kiialainen; Atanas Koulov; Björn Boll; Thomas Weiser; Thomas Singer; Antonius G Rolink; Antonio Iglesias
Journal:  Pharm Res       Date:  2015-01-29       Impact factor: 4.200

Review 2.  Apoptosis and its association with autoimmunity.

Authors:  J George; Y Adler; J Zhang; Y Shoenfeld; P Youinou
Journal:  Clin Rheumatol       Date:  1995-09       Impact factor: 2.980

3.  HS1 protein is differentially expressed in chronic lymphocytic leukemia patient subsets with good or poor prognoses.

Authors:  Cristina Scielzo; Paolo Ghia; Antonio Conti; Angela Bachi; Giuseppe Guida; Massimo Geuna; Massimo Alessio; Federico Caligaris-Cappio
Journal:  J Clin Invest       Date:  2005-06       Impact factor: 14.808

4.  Modulation of nonneutralizing HIV-1 gp41 responses by an MHC-restricted TH epitope overlapping those of membrane proximal external region broadly neutralizing antibodies.

Authors:  Jinsong Zhang; S Munir Alam; Hilary Bouton-Verville; Yao Chen; Amanda Newman; Shelley Stewart; Frederick H Jaeger; David C Montefiori; S Moses Dennison; Barton F Haynes; Laurent Verkoczy
Journal:  J Immunol       Date:  2014-01-24       Impact factor: 5.422

5.  Targeting the extracellular membrane-proximal domain of membrane-bound IgE by passive immunization blocks IgE synthesis in vivo.

Authors:  Stefan Feichtner; Daniela Inführ; Gertrude Achatz-Straussberger; Doris Schmid; Alexander Karnowski; Marinus Lamers; Claudio Rhyner; Reto Crameri; Gernot Achatz
Journal:  J Immunol       Date:  2008-04-15       Impact factor: 5.422

6.  Regulation of anti-DNA B cells in recombination-activating gene-deficient mice.

Authors:  H Xu; H Li; E Suri-Payer; R R Hardy; M Weigert
Journal:  J Exp Med       Date:  1998-10-05       Impact factor: 14.307
  6 in total

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