Literature DB >> 12814910

Alcohol intake after serotonin transporter inactivation in mice.

Sabah Kelaï1, Franck Aïssi, Klaus Peter Lesch, Charles Cohen-Salmon, Michel Hamon, Laurence Lanfumey.   

Abstract

Knock-out mice lacking the serotonin transporter [5-hydroxytryptamine transporter (5-HTT)] were used to assess the influence of 5-HT re-uptake on ethanol consumption. Under a free-choice paradigm, alcohol intake was lower in mutant than in wild-type mice, and pharmacological blockade of 5-HTT by fluoxetine reduced alcohol intake in wild-type mice only. These data confirm the inhibitory effect of 5-HTT inactivation on ethanol intake.

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Year:  2003        PMID： 12814910     DOI： 10.1093/alcalc/agg095

Source DB:  PubMed          Journal:  Alcohol Alcohol        ISSN： 0735-0414            Impact factor:   2.826


  15 in total

1.  Disruptions in serotonergic regulation of cortical glutamate release in primate insular cortex in response to chronic ethanol and nursery rearing.

Authors:  G M Alexander; J D Graef; J A Hammarback; B K Nordskog; E J Burnett; J B Daunais; A J Bennett; D P Friedman; S J Suomi; D W Godwin
Journal:  Neuroscience       Date:  2012-01-21       Impact factor: 3.590

Review 2.  Genes and Alcohol Consumption: Studies with Mutant Mice.

Authors:  J Mayfield; M A Arends; R A Harris; Y A Blednov
Journal:  Int Rev Neurobiol       Date:  2016       Impact factor: 3.230

3.  Affect-related behaviors in mice selectively bred for high and low voluntary alcohol consumption.

Authors:  Adem Can; Nicholas J Grahame; Todd D Gould
Journal:  Behav Genet       Date:  2011-10-12       Impact factor: 2.805

Review 4.  A pharmacological analysis of mice with a targeted disruption of the serotonin transporter.

Authors:  Meredith A Fox; Anne M Andrews; Jens R Wendland; Klaus-Peter Lesch; Andrew Holmes; Dennis L Murphy
Journal:  Psychopharmacology (Berl)       Date:  2007-08-22       Impact factor: 4.530

Review 5.  How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems.

Authors:  Dennis L Murphy; Meredith A Fox; Kiara R Timpano; Pablo R Moya; Renee Ren-Patterson; Anne M Andrews; Andrew Holmes; Klaus-Peter Lesch; Jens R Wendland
Journal:  Neuropharmacology       Date:  2008-09-11       Impact factor: 5.250

Review 6.  The brainstem and serotonin in the sudden infant death syndrome.

Authors:  Hannah C Kinney; George B Richerson; Susan M Dymecki; Robert A Darnall; Eugene E Nattie
Journal:  Annu Rev Pathol       Date:  2009       Impact factor: 23.472

7.  Combined Effects of Acamprosate and Escitalopram on Ethanol Consumption in Mice.

Authors:  Ada Man-Choi Ho; Yanyan Qiu; Yun-Fang Jia; Felipe S Aguiar; David J Hinton; Victor M Karpyak; Richard M Weinshilboum; Doo-Sup Choi
Journal:  Alcohol Clin Exp Res       Date:  2016-05-17       Impact factor: 3.455

8.  Congenital brain serotonin deficiency leads to reduced ethanol sensitivity and increased ethanol consumption in mice.

Authors:  Benjamin D Sachs; A Ayten Salahi; Marc G Caron
Journal:  Neuropharmacology       Date:  2013-09-22       Impact factor: 5.250

9.  Ethanol self-administration in serotonin transporter knockout mice: unconstrained demand and elasticity.

Authors:  R J Lamb; L C Daws
Journal:  Genes Brain Behav       Date:  2013-08-23       Impact factor: 3.449

Review 10.  Neuropharmacology of alcohol addiction.

Authors:  V Vengeliene; A Bilbao; A Molander; R Spanagel
Journal:  Br J Pharmacol       Date:  2008-03-03       Impact factor: 8.739
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