| Literature DB >> 12812486 |
Matthew D Hall1, Garry J Foran, Mei Zhang, Philip J Beale, Trevor W Hambley.
Abstract
Here we describe the use of X-ray absorption near edge spectroscopy (XANES) to provide information about the relative proportions of platinum(II) and platinum(IV) complexes by analyzing the XANES edge height. The intracellular reduction of platinum(IV) complexes in cancer cells has been observed directly, and the proportion of reduction after 2 h was found to correlate with the reduction potentials of the complexes.Entities:
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Year: 2003 PMID： 12812486 DOI： 10.1021/ja0354770
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419